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正常和青光眼犬眼内的肥大细胞数量。

Mast cell numbers in normal and glaucomatous canine eyes.

作者信息

Louden C, Render J A, Carlton W W

机构信息

Department of Pathology, College of Veterinary Medicine, Michigan State University, East Lansing 48824.

出版信息

Am J Vet Res. 1990 May;51(5):818-9.

PMID:2337285
Abstract

Numbers of mast cells in the cornea, sclera, choroid, ciliary body, iris, and retina of sections of globes from 35 clinically normal dogs and 34 dogs with secondary glaucoma was determined. Fixed globes were trimmed along a vertical midsagittal plane and embedded in paraffin. Tissue sections, approximately 6 microns thick, were stained with toluidine blue for identification of mast cells. In normal globes, most of the mast cells were observed in the anterior portion of the uvea, and fewer mast cells were seen in the choroid and sclera. Mast cells were not observed in the retina and were seldom observed in the cornea of dogs with or without glaucoma. In sections of glaucomatous globes, mast cells were distributed evenly in the uvea and sclera, and fewer mast cells were present than in normal globes, regardless of the cause of glaucoma.

摘要

测定了35只临床正常犬和34只继发性青光眼犬眼球切片中角膜、巩膜、脉络膜、睫状体、虹膜和视网膜中的肥大细胞数量。将固定好的眼球沿垂直矢状中平面修整并石蜡包埋。将约6微米厚的组织切片用甲苯胺蓝染色以识别肥大细胞。在正常眼球中,大多数肥大细胞见于葡萄膜前部,脉络膜和巩膜中可见的肥大细胞较少。在患有或未患青光眼的犬的视网膜中未观察到肥大细胞,在角膜中也很少观察到。在青光眼眼球切片中,肥大细胞在葡萄膜和巩膜中分布均匀,且无论青光眼病因如何,其数量均比正常眼球中的少。

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