So Kyungseop, Sung Eunju
Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean J Fam Med. 2013 Jan;34(1):11-8. doi: 10.4082/kjfm.2013.34.1.11. Epub 2013 Jan 28.
The prevalence of alcohol use disorder (AUD) is very high in Korea. To identify AUD in the busy practice setting, brevity of screening tools is very important. We derived the brief Alcohol Use Disorders Identification Test (AUDIT) and evaluated its performance as a brief screening test.
One hundred male drinkers from Kangbuk Samsung Hospital primary care outpatient clinic and psychiatric ward for alcoholism treatment completed questionnaires including the AUDIT, cut down, annoyed, guilty, eye-opener (CAGE), and National Alcoholism Screening Test (NAST) from April to July, 2007. AUD (alcohol abuse and dependence), defined by a physician in accordance with Diagnostic and Statistical Manual of Mental Disorders-IV, was used as a diagnostic criteria. To derive the brief AUDIT, factor analysis was performed using the principal component extraction method with a varimax rotated solution. Receiver operating characteristic (ROC) curve analysis was performed to investigate the discrimination ability of the brief AUDIT. Areas under the ROC curve were compared performance of screening questionnaires with 95% confidence intervals.
The derived brief AUDIT consists of 4 items: frequency of heavy drinking (item 3), impaired control over drinking (item 4), increased salience of drinking (item 5), and alcohol-related injury (item 9). Brief AUDIT exhibited an AUD screening accuracy better than CAGE, and equally to that of NAST. Areas under the ROC curves were 0.87 (0.80-0.94), 0.76 (0.66-0.85), and 0.81 (0.73-0.90) for the brief AUDIT, CAGE, and NAST for AUD, and 0.97 (0.95-0.99), 0.93 (0.88-0.98) and 0.93 (0.88-0.98) for alcohol dependence.
The new brief AUDIT seems to be effective in detecting male AUD in the primary care setting in Korea. Further evaluation for women and different age groups is needed.
酒精使用障碍(AUD)在韩国的患病率很高。在繁忙的临床环境中识别AUD,筛查工具的简洁性非常重要。我们推导了简短酒精使用障碍识别测试(AUDIT),并评估了其作为简短筛查测试的性能。
2007年4月至7月,来自江北三星医院初级保健门诊和酒精中毒治疗精神科病房的100名男性饮酒者完成了包括AUDIT、减少饮酒、烦恼、内疚、眼脸下垂(CAGE)和国家酒精中毒筛查测试(NAST)在内的问卷调查。由医生根据《精神疾病诊断与统计手册》第四版定义的AUD(酒精滥用和依赖)用作诊断标准。为了推导简短AUDIT,使用主成分提取方法和方差最大化旋转解进行因子分析。进行受试者操作特征(ROC)曲线分析以研究简短AUDIT的辨别能力。比较ROC曲线下面积与95%置信区间的筛查问卷性能。
推导的简短AUDIT由4个项目组成:重度饮酒频率(项目3)、饮酒控制受损(项目4)、饮酒显著性增加(项目5)和与酒精相关的伤害(项目9)。简短AUDIT在AUD筛查准确性方面表现优于CAGE,与NAST相当。简短AUDIT、CAGE和NAST用于AUD的ROC曲线下面积分别为0.87(0.80-0.94)、0.76(0.66-0.85)和0.81(0.73-0.90),用于酒精依赖的分别为0.97(0.95-0.99),0.93(0.88-0.98)和0.93(0.88-0.98)。
新的简短AUDIT似乎在韩国初级保健环境中检测男性AUD方面有效。需要对女性和不同年龄组进行进一步评估。