Szumiński Michał, Bakunowicz-Łazarczyk Alina
Klinika Okulistyki Dzieciecej z Ośrodkiem Leczenia Zeza, Uniwersyteckiego Dzieciecego Szpitala Klinicznego w Białymstoku.
Klin Oczna. 2012;114(3):180-3.
Studies on glaucoma markers have shown that assessment of thickness macular ganglion cell complex plays an important role in diagnosis of early stage open-angle glaucoma. There are no available data on thickness in ganglion cell complex in high myopic patients. We investigate thickness of macular ganglion cell complex in children with high myopia.
38 children (aged from 9 to 19 years), with high myopia (over -6.00 D) underwent full ophthalmological examination, including SD-OCT of the macula and optic disc. The reference group consisted of 38 emmetropic or slightly hyperopic children aged from 8 to 18 years old.
Superior and interior ganglion cell complex (GCC) thickness were significantly lower in high myopic group compared to reference group: p < 0.01, respectively for GCC Sup. median was 90 microm (range 67-108.5) and 95 microm (range 80-105.5); for GCC Inf. median was 91 microm (range: 67-109.5) and 98 microm (range 85-109). Positive correlation between GCC and Total RNFL was found.
In children with high myopia thinning of macular ganglion cell complex and retinal nerve fiber layer of the optic disc was found. These changes may be responsible for higher suspectibility of developing open-angle glaucoma in high myopic eyes. macular ganglion cell complex, high myopia, spectral optical coherence tomography.
关于青光眼标志物的研究表明，黄斑神经节细胞复合体厚度评估在早期开角型青光眼诊断中起着重要作用。目前尚无关于高度近视患者神经节细胞复合体厚度的可用数据。我们研究高度近视儿童黄斑神经节细胞复合体的厚度。
38名年龄在9至19岁之间的高度近视（超过-6.00 D）儿童接受了全面的眼科检查，包括黄斑和视盘的SD-OCT检查。对照组由38名年龄在8至18岁的正视或轻度远视儿童组成。
与对照组相比，高度近视组的上方和下方神经节细胞复合体（GCC）厚度显著降低：p < 0.01，GCC Sup.的中位数分别为90微米（范围67 - 108.5）和95微米（范围80 - 105.5）；GCC Inf.的中位数分别为91微米（范围：67 - 109.5）和98微米（范围85 - 109）。发现GCC与总视网膜神经纤维层之间存在正相关。
在高度近视儿童中发现黄斑神经节细胞复合体和视盘视网膜神经纤维层变薄。这些变化可能是高度近视眼发生开角型青光眼易感性较高的原因。黄斑神经节细胞复合体、高度近视、光谱光学相干断层扫描。
