Department of Pediatric Ophthalmology, Services, Sankara Eye Hospital, Harakere, Shimoga, Karnataka, India.
Department of Trauma and Cataract, Sankara Eye Hospital, Harakere, Shimoga, Karnataka, India.
Indian J Ophthalmol. 2021 Feb;69(2):290-295. doi: 10.4103/ijo.IJO_385_20.
The aim of this study was to estimate and compare the differences in ocular biometric measurements (OBMs), central macular thickness (CMT), and retinal nerve fiber layer thickness (RNFLT) between children with refractive errors and those with emmetropia.
A cross-sectional observational study of 205 children (334 eyes) aged between six and 18 years consisting of four groups (emmetropia, hypermetropia, myopia, and astigmatism) was carried out. Best-corrected visual acuity (BCVA), a detailed ocular examination, OBMs, spectral-domain optical coherence tomography (SD OCT) for RNFLT and CMT in both eyes were evaluated for each child.
Mean age of 205 children was 12.4 ± 3.2 years. 55.6% (n = 114) were girls and 44.4% (n = 91) were boys. There was a significant difference between the four groups for the parameters spherical equivalent (SE), keratometer readings K1and K2, axial length (AL), anterior chamber depth (ACD), vitreous chamber depth (VCD) and lens thickness (LT) (P < 0.0001). The mean central corneal thickness (CCT) was not significantly different between the four groups (P = 0.076). The mean RNFLT was thinner in the myopic group compared with the emmetropic group (P = 0.0048) There was no significant difference in the mean CMT across the four groups (P = 0.458).
The data obtained are helpful in providing the normative as well as a comparative database on OBMs, RNFLT and CMT of the pediatric population. This also facilitates evaluation of RNFLT and CMT measurements in children with amblyopia, optic neuropathies, glaucoma, macular and retinal diseases.
本研究旨在评估和比较屈光不正儿童与正视儿童的眼部生物测量（OBM）、中央黄斑厚度（CMT）和视网膜神经纤维层厚度（RNFLT）的差异。
进行了一项横断面观察性研究，共纳入 205 名 6 至 18 岁的儿童（334 只眼），分为 4 组（正视、远视、近视和散光）。对每个孩子进行最佳矫正视力（BCVA）、详细的眼部检查、OBM、双眼光谱域光相干断层扫描（SD OCT）的 RNFLT 和 CMT 评估。
205 名儿童的平均年龄为 12.4 ± 3.2 岁。55.6%（n = 114）为女孩，44.4%（n = 91）为男孩。四个组之间在球镜等效（SE）、角膜曲率计读数 K1 和 K2、眼轴长度（AL）、前房深度（ACD）、玻璃体腔深度（VCD）和晶状体厚度（LT）等参数上存在显著差异（P < 0.0001）。四个组之间中央角膜厚度（CCT）的平均值无显著差异（P = 0.076）。与正视组相比，近视组的平均 RNFLT 较薄（P = 0.0048）。四个组之间的平均 CMT 无显著差异（P = 0.458）。
获得的数据有助于为儿科人群提供 OBM、RNFLT 和 CMT 的正常参考值以及比较数据库。这也有助于评估弱视、视神经病变、青光眼、黄斑和视网膜疾病儿童的 RNFLT 和 CMT 测量值。
