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血管手术后戒烟情况的差异。

Variation in smoking cessation after vascular operations.

机构信息

Division of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH 60611, USA.

出版信息

J Vasc Surg. 2013 May;57(5):1338-44; quiz 1344.e1-4. doi: 10.1016/j.jvs.2012.10.130. Epub 2013 Jan 30.

Abstract

OBJECTIVE

Smoking is the most important modifiable risk factor for patients with vascular disease. The purpose of this study was to examine smoking cessation rates after vascular procedures and delineate factors predictive of postoperative smoking cessation.

METHODS

The Vascular Study Group of New England registry was used to analyze smoking status preoperatively and at 1 year after carotid endarterectomy, carotid artery stenting, lower extremity bypass, and open and endovascular abdominal aortic aneurysm repair between 2003 and 2009. Of 10,734 surviving patients after one of these procedures, 1755 (16%) were lost to follow-up and 1172 (11%) lacked documentation of their smoking status at follow-up. The remaining 7807 patients (73%) were available for analysis. Patient factors independently associated with smoking cessation were determined using multivariate analysis. The relative contribution of patient and procedure factors including treatment center were measured by χ-pie analysis. Variation between treatment centers was further evaluated by calculating expected rates of cessation and by analysis of means. Vascular Study Group of New England surgeons were surveyed regarding their smoking cessation techniques (85% response rate).

RESULTS

At the time of their procedure, 2606 of 7807 patients (33%) were self-reported current smokers. Of these, 1177 (45%) quit within the first year of surgery, with significant variation by procedure type (open abdominal aortic aneurysm repair, 50%; endovascular repair, 49%; lower extremity bypass, 46%; carotid endarterectomy, 43%; carotid artery stenting, 27%). In addition to higher smoking cessation rates with more invasive procedures, age >70 years (odds ratio [OR], 1.90; 95% confidence interval [CI], 1.30-2.76; P < .001) and dialysis dependence (OR, 2.38; 95% CI, 1.04-5.43; P = .04) were independently associated with smoking cessation, whereas hypertension (OR, 1.23; 95% CI, 1.00-1.51; P = .051) demonstrated a trend toward significance. Treatment center was the greatest contributor to smoking cessation, and there was broad variation in smoking cessation rates, from 28% to 62%, between treatment centers. Cessation rates were higher than expected in three centers and significantly lower than expected in two centers. Among survey respondents, 78% offered pharmacologic therapy or referral to a smoking cessation specialist, or both. The smoking cessation rate for patients of these surgeons was 48% compared with 33% in those who did not offer medications or referral (P < .001).

CONCLUSIONS

Patients frequently quit smoking after vascular surgery, and multiple patient-related and procedure-related factors contribute to cessation. However, we note significant influence of treatment center on cessation as well as broad variation in cessation rates between treatment centers. This variation indicates an opportunity for vascular surgeons to impact smoking cessation at the time of surgery.

摘要

目的

吸烟是血管疾病患者最重要的可改变风险因素。本研究的目的是调查血管手术后的戒烟率,并探讨预测术后戒烟的因素。

方法

利用血管研究小组新英格兰登记处,分析了 2003 年至 2009 年间颈动脉内膜切除术、颈动脉支架置入术、下肢旁路术以及开放和血管内腹主动脉瘤修复术后一年的吸烟状况。在接受其中一种手术的 10734 例存活患者中,1755 例(16%)失访,1172 例(11%)在随访时缺乏吸烟状况的记录。其余 7807 例(73%)患者可用于分析。使用多变量分析确定与戒烟相关的患者因素。使用 χ-pie 分析测量患者和手术因素(包括治疗中心)的相对贡献。通过计算预期戒烟率和均值分析进一步评估治疗中心之间的差异。对血管研究小组新英格兰的外科医生进行了有关其戒烟技术的调查(回应率 85%)。

结果

在手术时,7807 例患者中有 2606 例(33%)为自我报告的当前吸烟者。其中,1177 例(45%)在手术一年内戒烟,不同手术类型的戒烟率存在显著差异(开放式腹主动脉瘤修复术,50%;血管内修复术,49%;下肢旁路术,46%;颈动脉内膜切除术,43%;颈动脉支架置入术,27%)。除了更具侵入性的手术戒烟率更高外,年龄>70 岁(比值比[OR],1.90;95%置信区间[CI],1.30-2.76;P<0.001)和透析依赖(OR,2.38;95% CI,1.04-5.43;P=0.04)与戒烟独立相关,而高血压(OR,1.23;95% CI,1.00-1.51;P=0.051)则显示出显著的趋势。治疗中心是戒烟的最大贡献者,而且治疗中心之间的戒烟率差异很大,从 28%到 62%不等。三个中心的戒烟率高于预期,两个中心的戒烟率明显低于预期。在调查对象中,78%的人提供药物治疗或转诊至戒烟专家,或两者兼而有之。这些外科医生的患者戒烟率为 48%,而不提供药物治疗或转诊的患者为 33%(P<0.001)。

结论

血管手术后患者经常戒烟,多种与患者相关和手术相关的因素有助于戒烟。然而,我们注意到治疗中心对戒烟的影响以及治疗中心之间戒烟率的广泛差异。这种差异表明血管外科医生有机会在手术时影响戒烟。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db0/4279220/ff5a71aad39e/nihms522944f1.jpg

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