听神经瘤肿瘤体积的计算：ABC/2公式与面积测量法的比较
Calculating the tumor volume of acoustic neuromas: comparison of ABC/2 formula with planimetry method.
作者信息
Yu Yi-Lin, Lee Meei-Shyuan, Juan Chun-Jung, Hueng Dueng-Yuan
机构信息
Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
出版信息
Clin Neurol Neurosurg. 2013 Aug;115(8):1371-4. doi: 10.1016/j.clineuro.2012.12.029. Epub 2013 Feb 1.
OBJECTIVE
The ABC/2 equation is commonly applied to measure the volume of intracranial hematoma. However, the precision of ABC/2 equation in estimating the tumor volume of acoustic neuromas is less addressed. The study is to evaluate the accuracy of the ABC/2 formula by comparing with planimetry method for estimating the tumor volumes.
METHODS
Thirty-two patients diagnosed with acoustic neuroma received contrast-enhanced magnetic resonance imaging of brain were recruited. The volume was calculated by the ABC/2 equation and planimetry method (defined as exact volume) at the same time. The 32 patients were divided into three groups by tumor volume to avoid volume-dependent overestimation (<3 ml, 3-6 ml and >6 ml).
RESULTS
The tumor volume by ABC/2 method was highly correlated to that calculated by planimetry method using linear regression analysis (R2=0.985). Pearson correlation coefficient (r=0.993, p<0.001) demonstrates nearly perfect association between two methods.
CONCLUSIONS
The ABC/2 formula is an easy method in estimating the tumor volume of acoustic neuromas that is not inferior to planimetry method.
目的
ABC/2公式常用于测量颅内血肿体积。然而，ABC/2公式在估计听神经瘤肿瘤体积方面的精度较少被探讨。本研究旨在通过与平面测量法比较来评估ABC/2公式估计肿瘤体积的准确性。
方法
招募32例经诊断为听神经瘤的患者，均接受了脑部对比增强磁共振成像检查。同时采用ABC/2公式和平面测量法（定义为精确体积）计算体积。根据肿瘤体积将32例患者分为三组，以避免因体积依赖性导致的高估（<3 ml、3 - 6 ml和>6 ml）。
结果
通过线性回归分析，ABC/2法测得的肿瘤体积与平面测量法计算的结果高度相关（R2 = 0.985）。Pearson相关系数（r = 0.993，p < 0.001）表明两种方法之间具有近乎完美的相关性。
结论
ABC/2公式是一种估计听神经瘤肿瘤体积的简便方法，其准确性不低于平面测量法。
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