University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, USA.
Gastrointest Endosc. 2013 May;77(5):761-6. doi: 10.1016/j.gie.2012.11.041. Epub 2013 Feb 1.
Diagnostic yield of video capsule endoscopy (VCE) may be higher if it is performed closer to the time of overt obscure GI bleeding (OOGIB).
To evaluate the diagnostic yield of VCE and rate of therapeutic intervention for OOGIB for inpatients and outpatients with respect to timing of the intervention.
Retrospective cohort study.
Tertiary academic center.
Patients who had VCE for OOGIB between August 2008 and August 2010.
VCE for inpatients versus outpatients.
Diagnostic yield and rate of therapeutic intervention for inpatients versus outpatients.
One hundred forty-four inpatients (65 women) and 116 outpatients (49 women) were included. Diagnostic yield was 65.9% for inpatients versus 53.4% for outpatients (P = .054). Inpatients were divided into those who had VCE within 3 days (<3 days; n = 90) of admission versus after 3 days (>3 days; n = 54). Active bleeding and/or an angioectasia was found in 44.4% of the <3-day group compared with 27.8% of the >3-day group (P = .046) versus 25.8% of the outpatients. Therapeutic intervention was performed in 18.9% of the <3-day group versus 7.4% of the >3-day group (P = .046) versus 10.3% of outpatients. Diagnostic yield and therapeutic intervention rate between the >3-day group and outpatients were not significantly different. Length of stay (days) was less in the <3-day cohort, at 6.1 versus 10.3 in the >3-day cohort (P < .0001).
Long-term outcomes were not studied. This was a retrospective study.
Early deployment of VCE within 3 days of admission results in a higher diagnostic yield and therapeutic intervention rate and an associated reduction of length of stay.
如果在明显的胃肠道出血（OOGIB）发生时更接近时间进行视频胶囊内镜（VCE）检查，其诊断效果可能更高。
评估 VCE 对住院和门诊患者 OOGIB 的诊断效果，并根据干预时间评估 VCE 的治疗干预率。
回顾性队列研究。
三级学术中心。
2008 年 8 月至 2010 年 8 月期间因 OOGIB 进行 VCE 的患者。
住院患者与门诊患者 VCE。
住院患者与门诊患者的诊断效果和治疗干预率。
共纳入 144 例住院患者（65 例女性）和 116 例门诊患者（49 例女性）。住院患者的诊断效果为 65.9%，门诊患者为 53.4%（P=0.054）。住院患者分为入院后 3 天内（<3 天；n=90）和入院后 3 天以上（>3 天；n=54）进行 VCE 的两组。<3 天组中发现活动性出血和/或血管畸形的比例为 44.4%，而>3 天组为 27.8%（P=0.046），门诊患者为 25.8%。<3 天组进行治疗干预的比例为 18.9%，而>3 天组为 7.4%（P=0.046），门诊患者为 10.3%。>3 天组和门诊患者之间的诊断效果和治疗干预率无显著差异。<3 天组的住院时间（天）较短，为 6.1 天，而>3 天组为 10.3 天（P<0.0001）。
未研究长期结果。这是一项回顾性研究。
在入院后 3 天内早期使用 VCE 可提高诊断效果和治疗干预率，并缩短住院时间。
