Martinov Nestorov Jelena, Sokic-Milutinovic Aleksandra, Pavlovic Markovic Aleksandra, Krstic Miodrag
School of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Clinic for Gastroenterology and Hepatology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Diagnostics (Basel). 2024 Apr 23;14(9):862. doi: 10.3390/diagnostics14090862.
A retrospective study in patients who underwent video capsule endoscopy (VCE) between 2006 and 2016 was conducted in the Clinic for gastroenterology and Hepatology, University Clinical Center of Serbia. A total of 245 patients underwent VCE. In 198 patients the indication was obscure gastrointestinal bleeding (OGIB), with 92 patients having overt and the other 106 occult bleeding. The remaining 47 patients underwent VCE due to suspected small bowel (SB) disease (i.e., Von Hippel-Lindau syndrome, familial adenomatous polyposis, Peutz Jeghers syndrome, Crohn's disease, prolonged diarrhea, abdominal pain, congenital lymphangiectasia, protein-losing enteropathy, tumors, refractory celiac disease, etc.). VCE identified a source of bleeding in 38.9% of patients (in the obscure overt group in 48.9% of patients, and in the obscure occult group in 30.2% of patients). The most common findings were angiodysplasias, tumors, Meckel's diverticulum and Crohn's disease. In the smaller group of patients with an indication other than OGIB, 38.3% of patients had positive VCE findings. The most common indication is OGIB, and the best candidates are patients with overt bleeding; patients with IBD should be evaluated in this setting.
在塞尔维亚大学临床中心胃肠病学和肝病诊所，对2006年至2016年间接受视频胶囊内镜检查（VCE）的患者进行了一项回顾性研究。共有245例患者接受了VCE检查。198例患者的检查指征为不明原因的胃肠道出血（OGIB），其中92例为显性出血，另外106例为隐匿性出血。其余47例患者因疑似小肠疾病（即冯·希佩尔-林道综合征、家族性腺瘤性息肉病、佩-吉综合征、克罗恩病、长期腹泻、腹痛、先天性淋巴管扩张症、蛋白丢失性肠病、肿瘤、难治性乳糜泻等）接受了VCE检查。VCE在38.9%的患者中发现了出血源（在显性不明原因出血组中为48.9%的患者，在隐匿性不明原因出血组中为30.2%的患者）。最常见的发现是血管发育异常、肿瘤、梅克尔憩室和克罗恩病。在除OGIB以外有其他检查指征的较小患者组中，38.3%的患者VCE检查结果为阳性。最常见的检查指征是OGIB，最佳候选对象是显性出血患者；炎症性肠病患者应在此情况下接受评估。
