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[慢性支气管炎患者支气管肺泡灌洗液中的弹性蛋白酶和酸性磷酸酶活性]

[Elastase and acid phosphatase activity in bronchoalveolar lavage fluid during chronic bronchitis].

作者信息

Drozhennikov V A, Dykhanov I I, Ogloblina O G, Borisova A M, Beliakova A E, Krasil'nikov I V

出版信息

Biull Eksp Biol Med. 1990 Feb;109(2):130-2.

PMID:2337642
Abstract

The dynamics of acid phosphatase and granulocytic elastase activities in bronchoalveolar washings of 40 patients with chronic catarrhal bronchitis was studied. In case of effective cure, the activities of these enzymes were increased shortly on the 10-13 days from beginning of the cure. In order to study the nature of this enzymes, the additional researches were conducted. These researches demonstrated that the macrophages were the source of the acid phosphatase, and the neutrophils--elastase. The transitory increase of the activity of both enzymes is favourable prognostical sign of disease's course.

摘要

对40例慢性卡他性支气管炎患者支气管肺泡灌洗物中酸性磷酸酶和粒细胞弹性蛋白酶活性的动态变化进行了研究。在有效治愈的情况下,这些酶的活性在治疗开始后的第10 - 13天会短暂升高。为了研究这些酶的性质,进行了进一步的研究。这些研究表明,巨噬细胞是酸性磷酸酶的来源,而中性粒细胞是弹性蛋白酶的来源。两种酶活性的短暂升高是疾病进程的良好预后指标。

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