病毒性疾病患者的姐妹染色单体交换
Sister chromatid exchange in patients with viral disease.
作者信息
Kurvink K, Bloomfield C D, Cervenka J
机构信息
Division of Oral Pathology, University of Minnesota Health Sciences Center, Minneapolis 55455.
出版信息
Exp Cell Res. 1978 May;113(2):450-3. doi: 10.1016/0014-4827(78)90389-0.
Sister chromatid exchange (SCE) frequencies were studied in differentially stained chromosomes from lymphocytes of 17 patients with viral disease. The mean SCE score for the patients was 8.7 +/- 2.9 standard deviations. SCE scores were significantly elevated in the patients compared with the controls (p less than 0.01); however, variability in SCE means was observed in the patients. SCE elevations were also present in long term cultured Epstein Barr virus positive human B lymphocytes.
对17例病毒性疾病患者淋巴细胞中差异染色的染色体进行姐妹染色单体交换（SCE）频率研究。患者的平均SCE评分为8.7±2.9个标准差。与对照组相比，患者的SCE评分显著升高（p<0.01）；然而，在患者中观察到SCE平均值存在变异性。长期培养的爱泼斯坦-巴尔病毒阳性人类B淋巴细胞中也存在SCE升高。
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