Umetani T
First Department of Anatomy, Kobe University School of Medicine, Japan.
Brain Res. 1990 Jan 22;507(2):216-24. doi: 10.1016/0006-8993(90)90275-g.
The topography of the cerebellar nucleocortical projection was investigated in the albino rat by experiments employing an autoradiographic orthograde tracing method. The present results indicate that neurons in the deep cerebellar nuclei project to the granule cell layer of cerebellar cortex as mossy fiber terminals in an orderly way. Thus, the medial cerebellar nucleus projects mainly to the bilateral vermis with ipsilateral dominance. The interpositus and lateral cerebellar nuclei project mainly to the intermediate and lateral zones of the anterior and posterior lobes of the cortex, respectively. The paraflocculus and flocculus receive the nucleocortical projection from the caudal and ventral parts of the interpositus nuclei and the dentate nucleus. A mediolateral topography within each subdivision of the cerebellar nuclear complex was observed; the medial and lateral parts of the subdivision project to the more medial and lateral portions of the primary cortical targets of the subdivision, respectively.
采用放射自显影顺行追踪法，对白化大鼠小脑核皮质投射的拓扑结构进行了研究。目前的结果表明，小脑深部核团中的神经元以苔藓纤维终末的形式有序地投射到小脑皮质的颗粒细胞层。因此，小脑内侧核主要投射到双侧蚓部，以同侧为主。间位核和小脑外侧核分别主要投射到皮质前叶和后叶的中间区和外侧区。旁绒球和绒球接受来自间位核尾部和腹侧部以及齿状核的核皮质投射。在小脑核复合体的每个亚区内观察到了内侧到外侧的拓扑结构；该亚区的内侧和外侧部分分别投射到该亚区主要皮质靶点的更内侧和更外侧部分。
