Gould B B
J Comp Neurol. 1979 Mar 1;184(1):27-42. doi: 10.1002/cne.901840103.
The topography of the cerebellar nucleo-cortical projection was investigated in the cat by experiments employing the horseradish peroxidase (HRP) technique or by combined HRP-autoradiographic methods. The results of the HRP studies extend previous findings showing that neurons in the deep nuclei project to the cerebellar cortex in an orderly way. Thus, it appears that the cortex of the vermis-proper receives projections from neurons located predominately in the fastigial nucleus. Intermediate and lateral zones of mid-vermal cerebellar cortex are projected on by neurons located in the interposed and dentate nuclei. Crus II receives input from neurons located predominately in the dentate nucleus, while the paramedian lobule is projected on by neurons located in a large postero-dorsal sector of the interposed nucleus and in a smaller medial strip of the dentate nucleus. Neurons in the ventral part of the dentate nucleus and the lateral part of the interposed nucleus send fibers to the paraflocculus. The nucleo-cortical pathway to the flocculus and nodulus arises largely from a population of neurons located in a ventral region stretching from the medial border of the dentate nucleus to the lateral border of the fastigial nucleus. The results of experiments using the combined HRP-autoradiographic method show that clusters of neurons in the deep cerebellar nuclei project back to the cerebellar cortical areas from which they receive input, establishing a fairly precise feedback loop between the cerebellar cortex and deep nuclei.
运用辣根过氧化物酶（HRP）技术或HRP - 放射自显影联合方法，对猫小脑核 - 皮质投射的拓扑结构进行了研究。HRP研究结果扩展了先前的发现，即深部核团中的神经元以有序方式投射至小脑皮质。因此，蚓部皮质似乎主要接收来自顶核中神经元的投射。小脑蚓部皮质的中间区和外侧区由间位核和齿状核中的神经元投射。小脑 Crus II 主要接收来自齿状核中神经元的输入，而旁正中小叶则由间位核的一个大的后背部区域和齿状核的一个较小的内侧条带中的神经元投射。齿状核腹侧部分和间位核外侧部分的神经元向旁绒球发送纤维。至绒球和小结的核 - 皮质通路主要起源于一群位于从齿状核内侧边界延伸至顶核外侧边界的腹侧区域的神经元。使用HRP - 放射自显影联合方法的实验结果表明，小脑深部核团中的神经元簇投射回它们接收输入的小脑皮质区域，在小脑皮质和深部核团之间建立了相当精确的反馈回路。
