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泰国人群中肌少症的流行情况及其相关因素。

Prevalence of sarcopenia and associated factors among Thai population.

机构信息

Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

出版信息

J Bone Miner Metab. 2013 May;31(3):346-50. doi: 10.1007/s00774-013-0422-4. Epub 2013 Feb 2.

Abstract

The purpose of this study was to determine the prevalence of sarcopenia using the skeletal muscle index (SMI) criteria in the Thai population. The secondary objective was to demonstrate factors influencing low SMI in this population. Femoral neck bone mass density (BMD) was measured by dual-energy X-ray absorptiometry (GE Lunar, Madison, WI, USA) in 435 urban and 397 rural subjects (334 men and 498 women) between 20 and 84 years of age. Body mass index (BMI) was calculated from weight and height. The respective prevalence of sarcopenia among men and women was 35.33 % (95 % CI, 29.91, 40.41) and 34.74 % (95 % CI, 30.56, 39.10). Factors associated with sarcopenia using multiple logistic regression analyses in both sexes were (a) living in the city, (b) higher BMI, and (c) older age. Living in an urban area was the strongest factor, with an odds ratio (OR) of 17.26 ± 7.12 (95 % CI, 7.68, 38.76) in men and 8.62 ± 2.74 (95 % CI, 4.62, 16.05) in women (p < 0.05). The prevalence rate ratio for persons living in urban compared to rural areas was 2.01 (95 % CI, 1.14, 3.53) in men and 1.69 (95 % CI, 1.31, 2.17) in women (p < 0.05). Sarcopenia, as based on SMI, occurs frequently in the Thai population and increases with age. The prevalence of sarcopenia is particularly high among pre-retirement women (50-59 years of age) whereas the number of men with sarcopenia gradually rises with age. An urban environment is the most predictive factor for sarcopenia, followed by high BMI and age. Given the aging population, early recognition of this condition can be beneficial for prevention of an epidemic of sarcopenia-related disability.

摘要

本研究旨在通过骨骼肌指数 (SMI) 标准确定泰国人群中肌少症的流行率。次要目标是证明影响该人群低 SMI 的因素。通过双能 X 射线吸收法(GE Lunar,Madison,WI,USA)在 435 名城市和 397 名农村受试者(334 名男性和 498 名女性)中测量股骨颈骨密度(BMD)。体重指数(BMI)由体重和身高计算得出。男性和女性的肌少症患病率分别为 35.33%(95%CI,29.91,40.41)和 34.74%(95%CI,30.56,39.10)。在两性中,使用多因素逻辑回归分析与肌少症相关的因素为(a)居住在城市,(b)较高的 BMI,和(c)年龄较大。居住在城市地区是最强的因素,男性的优势比(OR)为 17.26±7.12(95%CI,7.68,38.76),女性为 8.62±2.74(95%CI,4.62,16.05)(p<0.05)。与农村地区相比,居住在城市地区的人的患病率比为 2.01(95%CI,1.14,3.53),女性为 1.69(95%CI,1.31,2.17)(p<0.05)。基于 SMI 的肌少症在泰国人群中较为常见,并随年龄增长而增加。肌少症的患病率在退休前女性(50-59 岁)中尤其高,而男性中肌少症的人数随着年龄的增长逐渐增加。城市环境是肌少症最具预测性的因素,其次是高 BMI 和年龄。鉴于人口老龄化,早期识别这种情况有助于预防肌少症相关残疾的流行。

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