Mukora-Mutseyekwa Fadzai Nn, Chadambuka Elizabeth M
Faculty of Health Sciences, Africa University, Mutare, Zimbabwe.
Patient Prefer Adherence. 2013;7:65-70. doi: 10.2147/PPA.S40295. Epub 2013 Jan 17.
This study investigated the level of drug adherence among hypertensive outpatients at a tertiary hospital in Zimbabwe. Specific objectives included measurement of blood pressure (BP) control achievement, estimating prevalence of drug adherence behavior, and establishing the association between drug adherence behavior and achievement of BP control.
An analytic cross sectional design was applied on a convenience sample of 102 participants using an interviewer administered questionnaire. Self-reported adherence was assessed using the Morisky Medication Adherence Scale.
The median age of participants was 68.5 years (Q(1) 61;Q(3) 76). The majority were female (n = 71;69.6%). BP control (< 140/90 mmHg) was achieved in 52% (n = 53). Self-reported drug adherence was 40.2% (n = 42). After multivariate logistic regression analysis, participants with normal BP measurements were more than three times as likely to report maximal adherence to prescribed drug schedules (odds ratio 3.37; 95% confidence interval: 1.38-.24).
Poor drug adherence behavior prevails among hypertensive outpatients. This contributes to poor achievement of BP control. The hospital is recommended to set up a specialized hypertension clinic in the Out-patients' Department where an intensified health education package can be introduced as well as community awareness programs on the importance of medication adherence.
本研究调查了津巴布韦一家三级医院高血压门诊患者的药物依从性水平。具体目标包括测量血压控制达标情况、估计药物依从行为的患病率,以及确定药物依从行为与血压控制达标之间的关联。
采用分析性横断面设计,对102名参与者的便利样本使用访谈者管理的问卷进行调查。使用Morisky药物依从性量表评估自我报告的依从性。
参与者的年龄中位数为68.5岁(Q(1) 61;Q(3) 76)。大多数为女性(n = 71;69.6%)。52%(n = 53)的患者实现了血压控制(< 140/90 mmHg)。自我报告的药物依从率为40.2%(n = 42)。经过多因素逻辑回归分析,血压测量正常的参与者报告最大程度遵守规定药物治疗方案的可能性是其他参与者的三倍多(优势比3.37;95%置信区间:1.38 - 8.24)。
高血压门诊患者中药物依从行为较差的情况普遍存在。这导致血压控制达标情况不佳。建议医院在门诊部设立专门的高血压诊所,引入强化健康教育套餐以及关于药物依从性重要性的社区宣传项目。