Omar Saeed M, Elnour Osama, Adam Gamal K, Osman Osman E, Adam Ishag
Faculty of Medicine, Gadarif University, Gadarif, Sudan.
Faculty of Medicine, Omdurman University, Omdurman, Sudan.
BMC Cardiovasc Disord. 2018 Feb 7;18(1):26. doi: 10.1186/s12872-018-0769-5.
The rate of blood pressure (BP) control in adult hypertensive patients is poor and the reasons for poor control of BP pressure are not fully understood globally. This study aimed to assess the rate and factors associated with BP control in adult hypertensive patients in Sudan.
A hospital-based cross-sectional study was conducted in adult hypertensive Sudanese patients at Gadarif Hospital in eastern Sudan from November 2016 to March 2017. Information on sociodemographic characteristics of the participants, comorbidities, antihypertensive medication, and adherence to antihypertensive medication was gathered from patients using a questionnaire. Fasting cholesterol and triglyceride levels were measured.
A total of 380 patients were enrolled. Of them, 234 (61.6%) were women. The mean (SD) age of the participants was 57.8 (11.1) years (range: 25-93 years). Over one-third (n = 147, 38.7%) of the participants were taking more than one antihypertensive medication. Approximately one-third (29.5%) of the participants were non-adherent to medication. The rate of BP control was 45.3%. In binary logistic regression analyses, age, sex, physical inactivity, adding salt to food, drinking coffee, body mass index, and the lipid profile were not associated with uncontrolled BP. However, non-adherence to medication was the main factor associated with uncontrolled BP (odds ratio = 5.29, 95% confidence interval = 3.16-8.83, P < 0.001).
Almost half of hypertensive patients in follow-up have uncontrolled BP, mainly due to non-adherence to medicine. We recommend further research on drug adherence to improve the rate of BP control in this setting (Gadarif) of the Sudan.
成年高血压患者的血压控制率较低，全球范围内对血压控制不佳的原因尚未完全了解。本研究旨在评估苏丹成年高血压患者的血压控制率及相关因素。
2016年11月至2017年3月，在苏丹东部加达里夫医院对成年高血压患者进行了一项基于医院的横断面研究。通过问卷调查收集参与者的社会人口学特征、合并症、抗高血压药物及抗高血压药物依从性等信息。测量空腹胆固醇和甘油三酯水平。
共纳入380例患者。其中，234例（61.6%）为女性。参与者的平均（标准差）年龄为57.8（11.1）岁（范围：25 - 93岁）。超过三分之一（n = 147，38.7%）的参与者服用不止一种抗高血压药物。约三分之一（29.5%）的参与者不依从药物治疗。血压控制率为45.3%。在二元逻辑回归分析中，年龄、性别、身体活动不足、食物加盐、喝咖啡、体重指数和血脂谱与血压未控制无关。然而，不依从药物治疗是血压未控制的主要相关因素（比值比 = 5.29，95%置信区间 = 3.16 - 8.83，P < 0.001）。
几乎一半的随访高血压患者血压未得到控制，主要原因是不依从药物治疗。我们建议在苏丹的这一地区（加达里夫）进一步开展关于药物依从性的研究，以提高血压控制率。
