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东非撒哈拉以南地区血压控制不佳的原因:从初级保健、专业人员、患者和公共卫生政策四个方面探讨改善血压控制的方法:范围综述。

Reasons for poor blood pressure control in Eastern Sub-Saharan Africa: looking into 4P's (primary care, professional, patient, and public health policy) for improving blood pressure control: a scoping review.

机构信息

Department of Pharmacy, Arba Minch University College of Medicine and Health Sciences, P.O. Box 21, Arba Minch, Ethiopia.

Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

BMC Cardiovasc Disord. 2021 Mar 4;21(1):123. doi: 10.1186/s12872-021-01934-6.

Abstract

AIM

Hypertension control in Sub-Saharan Africa (SSA) is the worst (less than one out of ten) when compared to the rest of the world. Therefore, this scoping review was conducted to identify and describe the possible reasons for poor blood pressure (BP) control based on 4Ps' (patient, professional, primary healthcare system, and public health policy) factors.

METHODS

PRISMA extension for scoping review protocol was used. We systematically searched articles written in the English language from January 2000 to May 2020 from the following databases: PubMed/Medline, Embase, Scopus, Web of Science, and Google scholar.

RESULTS

Sixty-eight articles were included in this scoping review. The mean prevalence of hypertension, BP control, and patient adherence to prescribed medicines were 20.95%, 11.5%, and 60%, respectively. Only Kenya, Malawi, and Zambia out of ten countries started annual screening of the high-risk population for hypertension. Reasons for nonadherence to prescribed medicines were lack of awareness, lack of access to medicines and health services, professional inertia to intensify drugs, lack of knowledge on evidence-based guidelines, insufficient government commitment, and specific health behaviors related laws. Lack of screening for high-risk patients, non-treatment adherence, weak political commitment, poverty, maternal and child malnutrition were reasons for the worst BP control.

CONCLUSION

In conclusion, the rate of BP treatment, control, and medication adherence was low in Eastern SSA. Screening for high-risk populations was inadequate. Therefore, it is crucial to improve government commitment, patient awareness, and access to medicines, design country-specific annual screening programs, and empower clinicians to follow individualized treatment and conduct medication adherence research using more robust tools.

摘要

目的

与世界其他地区相比,撒哈拉以南非洲(SSA)的高血压控制情况最差(十分之一以下)。因此,进行了这项范围界定综述,以根据 4Ps(患者、专业人员、初级医疗保健系统和公共卫生政策)因素,确定并描述血压控制不佳的可能原因。

方法

使用 PRISMA 扩展的范围界定综述方案。我们从以下数据库系统地搜索了 2000 年 1 月至 2020 年 5 月以英文撰写的文章:PubMed/Medline、Embase、Scopus、Web of Science 和 Google Scholar。

结果

这项范围界定综述共纳入 68 篇文章。高血压、血压控制和患者对规定药物的依从性的平均患病率分别为 20.95%、11.5%和 60%。在十个国家中,只有肯尼亚、马拉维和赞比亚开始对高血压高危人群进行年度筛查。不遵守规定药物的原因是缺乏意识、缺乏获得药物和卫生服务的机会、专业人员不愿加强药物治疗、缺乏循证指南知识、政府承诺不足以及与特定卫生行为相关的法律。缺乏对高危患者的筛查、不遵医嘱治疗、政治承诺不足、贫困、母婴营养不良是导致血压控制最差的原因。

结论

综上所述,东非 SSA 的血压治疗、控制和药物依从率较低。高危人群筛查不足。因此,必须提高政府承诺、患者意识和获得药物的机会,设计针对特定国家的年度筛查计划,并赋予临床医生权力,使其遵循个性化治疗,并使用更强大的工具开展药物依从性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0e5/7971125/159974baf6d0/12872_2021_1934_Fig1_HTML.jpg

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