安定和阿司匹林对小鼠C3H10T1/2细胞中X射线诱导转化的抑制作用。
Suppression of x-ray induced transformation by Valium and aspirin in mouse C3H10T1/2 cells.
作者信息
Radner B S, Kennedy A R
机构信息
Harvard School of Public Health, Boston, MA 02115.
出版信息
Cancer Lett. 1990 May 15;51(1):49-57. doi: 10.1016/0304-3835(90)90230-u.
PMID:2337898
Abstract
Two commonly used drugs, Valium (diazepam) and Aspirin (acetylsalicyclic acid), were shown to suppress X-ray induced transformation in mouse C3H/10T1/2 cells. Valium was studied in an ethanol solution. Aspirin, which is soluble in both water and ethanol, was active only in the ethanol solution. Both drugs were effective only when present throughout the entire assay period.
摘要
两种常用药物，安定（地西泮）和阿司匹林（乙酰水杨酸），已被证明可抑制X射线诱导的小鼠C3H/10T1/2细胞转化。安定在乙醇溶液中进行研究。阿司匹林可溶于水和乙醇，但仅在乙醇溶液中具有活性。两种药物仅在整个检测期间都存在时才有效。
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