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单独用电干燥术和刮除术治疗后侵袭性组织学类型基底细胞癌的复发率。

Recurrence rates of aggressive histologic types of basal cell carcinoma after treatment with electrodesiccation and curettage alone.

机构信息

School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota, USA.

出版信息

Dermatol Surg. 2013 May;39(5):719-25. doi: 10.1111/dsu.12122. Epub 2013 Feb 4.

Abstract

BACKGROUND

Basal cell carcinoma (BCC) is the most common cancer in Caucasians. Treatment options include electrodesiccation and curettage (EDC), surgical excision, and Mohs micrographic surgery (MMS). EDC is standard for smaller BCCs in low-risk locations with nonaggressive histologic subtypes. Larger BCCs in higher-risk locations and aggressive histologic subtypes are treated using surgical excision or MMS. We found no studies reporting recurrence rates for aggressive BCC subtypes treated using EDC alone.

OBJECTIVE

To determine recurrence rates of histologically aggressive BCC treated using EDC.

METHODS AND MATERIALS

This population-based, retrospective case study reviewed 37 primary infiltrative, desmoplastic, morpheaform, or micronodular BCCs in 34 patients treated with EDC. Recurrence was defined as reappearance of BCC within the boundaries of or contiguous to the scar resulting from initial treatment.

RESULTS

Of 37 primary aggressive BCCs, 10 recurred within 3.3 years. Average primary tumor diameter was 0.69 cm. Average primary tumor diameter was 0.73 cm for those that recurred and 0.67 cm for those that did not recur. Six recurrences were in high-risk areas, three in moderate-risk areas, and one in a low-risk area.

CONCLUSION

We report a 27% recurrence rate for histologically aggressive BCCs treated using EDC alone with median 6.5 years follow-up.

摘要

背景

基底细胞癌(BCC)是白种人中最常见的癌症。治疗选择包括电干燥和刮除术(EDC)、手术切除和Mohs 显微外科手术(MMS)。EDC 是低危部位、非侵袭性组织学亚型的较小 BCC 的标准治疗方法。高危部位和侵袭性组织学亚型的较大 BCC 则采用手术切除或 MMS 治疗。我们没有发现报告单独使用 EDC 治疗侵袭性 BCC 亚型的复发率的研究。

目的

确定使用 EDC 治疗的侵袭性 BCC 的组织学复发率。

方法和材料

这项基于人群的回顾性病例研究回顾了 34 名患者的 37 例原发性浸润性、硬化性、硬皮病样或微结节性 BCC,这些患者均接受了 EDC 治疗。复发定义为在初始治疗引起的瘢痕边界内或与其相邻处 BCC 的再次出现。

结果

在 37 例原发性侵袭性 BCC 中,有 10 例在 3.3 年内复发。原发性肿瘤平均直径为 0.69cm。复发患者的平均原发性肿瘤直径为 0.73cm,未复发患者的平均原发性肿瘤直径为 0.67cm。6 例复发发生在高危区域,3 例发生在中危区域,1 例发生在低危区域。

结论

我们报告了一项单独使用 EDC 治疗侵袭性 BCC 的 27%复发率,中位随访时间为 6.5 年。

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