Brain and Creativity Institute, University of Southern California, CA 90089-2520, USA.
Neuroimage. 2013 May 15;72:280-6. doi: 10.1016/j.neuroimage.2013.01.056. Epub 2013 Feb 4.
Studies of prefrontal cortex (PFC) lesion patients suggest that information conveying high immediacy, certainty, or tangibility engages the more posterior part of the PFC, whereas information that is more abstract or complex engages the anterior part. We examined whether the anterior and posterior subdivisions of the PFC have distinct roles in processing temporal information during decision making in healthy individuals. We hypothesized that the more the locus of activation is in the posterior (as opposed to anterior) PFC, the more the decision maker will be affected by recent information at the expense of past outcomes. Participants performed a complex decision task while their PFC activity was monitored using fMRI. Results indicate that individual differences in the effect of recent outcomes correspond to differences in the locus of activation, with elevated recency associated with more posterior loci of activation.
前额叶皮层（PFC）损伤患者的研究表明，传达高即时性、确定性或有形性的信息会激活 PFC 的更靠后的部分，而更抽象或复杂的信息则会激活 PFC 的更靠前的部分。我们研究了在健康个体进行决策时，PFC 的前、后两部分是否在处理时间信息方面具有不同的作用。我们假设，激活的部位越靠后（相对于靠前），决策者受近期信息影响的程度就越大，而忽略过去的结果。参与者在执行一项复杂的决策任务时，我们使用 fMRI 监测他们的 PFC 活动。结果表明，近期结果的影响的个体差异与激活部位的差异相对应，随着最近结果的出现，激活部位更靠后。
