Yano Shuichi
National Hospital Organization Matsue Medical Center, Matsue, Japan.
BMJ Case Rep. 2013 Feb 4;2013:bcr2012008171. doi: 10.1136/bcr-2012-008171.
Pulmonary injuries due to S-1 have been reported, and these reports have shown an increase in lung cancer following the increased usage of S-1 in treating lung cancer. We report the first case of lung injury due to S-1 in combination with pneumocystis pneumonia (PCP), because the radiological findings and clinical courses were compatible with S-1-induced lung injury combined with PCP. We should consider that S-1 might induce lung injuries which might occur with PCP, especially with a history of drug-induced or radiation-induced lung injuries.
已有关于S-1所致肺损伤的报道，且这些报道显示，在肺癌治疗中S-1使用量增加后肺癌有所增多。我们报告首例S-1联合肺孢子菌肺炎（PCP）所致的肺损伤病例，因为影像学表现和临床病程符合S-1诱导的肺损伤合并PCP。我们应考虑S-1可能诱发与PCP相关的肺损伤，尤其是有药物性或放射性肺损伤病史的情况。
