Kanatas Anastasios, Velikova Galina, Roe Brenda, Horgan Kieran, Ghazali Naseem, Shaw Richard J, Rogers Simon N
Leeds Teaching Hospitals and St James Institute of Oncology, Leeds General Infirmary, Leeds, United Kingdom.
Tumori. 2012 Nov;98(6):678-88. doi: 10.1177/030089161209800602.
Patient-reported outcomes (PROs) include areas of health-related quality of life but also broader concepts such as patient satisfaction with care. The aim of this review is to give an account of all instruments with potential use in patients with a history of treatment for breast cancer (including surgery, chemotherapy and/or radiotherapy) with evidence of validation in the breast cancer population.
All instruments included in this review were identified as PRO measures measuring breast-related quality of life and/or satisfaction that had undergone development and validation with breast oncology patients. We specifically looked for PRO measures examining patient satisfaction and/or quality of life after breast cancer treatment. Following an evaluation of 323 papers, we identified 15 instruments that were able to satisfy our inclusion criteria.
These instruments are the EORTC QOL-C30 and QLQ-BR23 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Breast Cancer Module), the FACT-B (Functional Assessment of Cancer Therapy-Breast Cancer), the SLDS-BC (Satisfaction with Life Domains Scale for Breast Cancer), the BIBCQ (Body Image after Breast Cancer Questionnaire), the HIBS (Hopwood Body Image Scale), the PBIS (Polivy Body Image Scale), the MBROS (Michigan Breast Reconstruction Outcomes Study) Satisfaction and Body Image Questionnaires, the BREAST-Q, the BCTOS (Breast Cancer Treatment Outcome Scale), the BCQ, the FACT-ES (Functional Assessment of Cancer Therapy-Endocrine System), the MAS (Mastectomy Attitude Scale), and the Breast Cancer Prevention Trial Symptom Checklist (BCPT).
Suggestions for future directions include (1) to use and utilize validated instruments tailored to clinical practice; (2) to develop a comprehensive measurement of surgical outcome requiring the combination of objective and subjective measures; (3) to aim for a compromise between these two competing considerations in the form of a scale incorporating both generalizability in cancer-related QOL and specificity in breast cancer issues.
患者报告结局（PROs）涵盖与健康相关的生活质量领域，也包括诸如患者对医疗护理满意度等更广泛的概念。本综述的目的是介绍所有可能用于有乳腺癌治疗史（包括手术、化疗和/或放疗）患者且在乳腺癌人群中有验证证据的工具。
本综述纳入的所有工具均被确定为测量与乳房相关的生活质量和/或满意度的PRO测量方法，这些方法已经过乳腺癌患者的开发和验证。我们特别寻找用于检查乳腺癌治疗后患者满意度和/或生活质量的PRO测量方法。在评估了323篇论文后，我们确定了15种能够满足我们纳入标准的工具。
这些工具包括欧洲癌症研究与治疗组织生活质量问卷核心30项（EORTC QOL-C30）和乳腺癌模块23项（QLQ-BR23）、癌症治疗功能评价量表-乳腺癌（FACT-B）、乳腺癌生活领域满意度量表（SLDS-BC）、乳腺癌后身体意象问卷（BIBCQ）、霍普伍德身体意象量表（HIBS）、波利维身体意象量表（PBIS）、密歇根乳房重建结果研究满意度和身体意象问卷（MBROS）、BREAST-Q、乳腺癌治疗结果量表（BCTOS）、乳腺癌问卷（BCQ）、癌症治疗功能评价量表-内分泌系统（FACT-ES）、乳房切除术态度量表（MAS）以及乳腺癌预防试验症状清单（BCPT）。
对未来方向的建议包括：（1）使用和利用针对临床实践量身定制的经过验证的工具；（2）开发一种需要结合客观和主观测量的手术结果综合测量方法；（3）以一种量表的形式在这两个相互竞争的考量之间达成妥协，该量表既要包含癌症相关生活质量的普遍性，又要包含乳腺癌问题的特异性。
