White P Lewis, Jones Tim, Whittle Katie, Watkins Joanne, Barnes Rosemary A
Public Health Wales, Microbiology Cardiff, University Hospital of Wales (UHW), Cardiff, United Kingdom.
Clin Vaccine Immunol. 2013 Apr;20(4):636-8. doi: 10.1128/CVI.00730-12. Epub 2013 Feb 6.
Diagnostic galactomannan (GM) enzyme immunoassay (EIA) testing is formally validated only for serum, though in practice, plasma is occasionally tested. It is assumed, but not confirmed, that results will be comparable to those for serum. GM EIA when testing plasma was evaluated, providing sensitivity (85.7%) and specificity (85.4%) comparable to those for serum. Plasma index values were higher than those for serum; if plasma GM EIA were used to define probable cases, four additional cases would have been diagnosed.
诊断性半乳甘露聚糖(GM)酶免疫测定(EIA)检测仅在血清方面得到正式验证,不过在实际操作中,偶尔也会检测血浆。虽然假定血浆检测结果与血清检测结果具有可比性,但尚未得到证实。对检测血浆时的GM EIA进行了评估,其灵敏度(85.7%)和特异性(85.4%)与血清检测结果相当。血浆指数值高于血清;如果使用血浆GM EIA来定义可能的病例,将会多诊断出4例病例。