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本文引用的文献

1
Probable invasive aspergillosis without prespecified radiologic findings: proposal for inclusion of a new category of aspergillosis and implications for studying novel therapies.无预设影像学发现的疑似侵袭性曲霉病:纳入一种新曲霉病分类的建议及其对研究新型疗法的影响。
Clin Infect Dis. 2010 Dec 1;51(11):1273-80. doi: 10.1086/657065. Epub 2010 Oct 29.
2
Clinical impact of enhanced diagnosis of invasive fungal disease in high-risk haematology and stem cell transplant patients.高危血液学及干细胞移植患者侵袭性真菌病强化诊断的临床影响
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Galactomannan detection for invasive aspergillosis in immunocompromized patients.免疫功能低下患者侵袭性曲霉病的半乳甘露聚糖检测
Cochrane Database Syst Rev. 2008 Oct 8(4):CD007394. doi: 10.1002/14651858.CD007394.
4
Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group.欧洲癌症研究与治疗组织/侵袭性真菌感染合作组和美国国立过敏与传染病研究所真菌病研究组(EORTC/MSG)共识组对侵袭性真菌病的修订定义。
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Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus.定义癌症和造血干细胞移植免疫受损患者中的机会性侵袭性真菌感染:一项国际共识。
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检测血清和血浆样本时半乳甘露聚糖酶免疫测定性能水平的比较。

Comparison of galactomannan enzyme immunoassay performance levels when testing serum and plasma samples.

作者信息

White P Lewis, Jones Tim, Whittle Katie, Watkins Joanne, Barnes Rosemary A

机构信息

Public Health Wales, Microbiology Cardiff, University Hospital of Wales (UHW), Cardiff, United Kingdom.

出版信息

Clin Vaccine Immunol. 2013 Apr;20(4):636-8. doi: 10.1128/CVI.00730-12. Epub 2013 Feb 6.

DOI:10.1128/CVI.00730-12
PMID:23389933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3623416/
Abstract

Diagnostic galactomannan (GM) enzyme immunoassay (EIA) testing is formally validated only for serum, though in practice, plasma is occasionally tested. It is assumed, but not confirmed, that results will be comparable to those for serum. GM EIA when testing plasma was evaluated, providing sensitivity (85.7%) and specificity (85.4%) comparable to those for serum. Plasma index values were higher than those for serum; if plasma GM EIA were used to define probable cases, four additional cases would have been diagnosed.

摘要

诊断性半乳甘露聚糖(GM)酶免疫测定(EIA)检测仅在血清方面得到正式验证,不过在实际操作中,偶尔也会检测血浆。虽然假定血浆检测结果与血清检测结果具有可比性,但尚未得到证实。对检测血浆时的GM EIA进行了评估,其灵敏度(85.7%)和特异性(85.4%)与血清检测结果相当。血浆指数值高于血清;如果使用血浆GM EIA来定义可能的病例,将会多诊断出4例病例。