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纳豆（发酵大豆）提取物可延长秀丽隐杆线虫的成虫寿命。

Natto (fermented soybean) extract extends the adult lifespan of Caenorhabditis elegans.

作者信息

Ibe Sachie, Kumada Kaoru, Yoshida Keiko, Otobe Kazunori

机构信息

Oyamatofu Co., Ltd., Shirone, Isehara, Kanagawa, Japan.

出版信息

Biosci Biotechnol Biochem. 2013;77(2):392-4. doi: 10.1271/bbb.120726. Epub 2013 Feb 7.

DOI:10.1271/bbb.120726
PMID:23391920
Abstract

We investigated the effects of a water extract of natto on the aging of the nematode Caenorhabditis elegans. The water extract significantly prolonged the adult lifespan of the wild-type worms and rendered them resistant to oxidative and thermal stress. In addition, treatment with natto extract significantly delayed the accumulation of lipofuscin, a characteristic of aging cells. Our findings suggest that components of natto have a beneficial anti-aging effect in vivo.

摘要

我们研究了纳豆水提取物对线虫秀丽隐杆线虫衰老的影响。该水提取物显著延长了野生型线虫的成虫寿命，并使其对氧化应激和热应激具有抗性。此外，用纳豆提取物处理显著延迟了脂褐素的积累，脂褐素是衰老细胞的一个特征。我们的研究结果表明，纳豆成分在体内具有有益的抗衰老作用。

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