硫酸镁对重度子痫前期孕妇胎儿脐动脉和大脑中动脉多普勒参数的影响。
Effect of magnesium sulfate on Doppler parameters of fetal umbilical and middle cerebral arteries in women with severe preeclampsia.
作者信息
Farshchian Nazanin, Rezavand Negin, Mohammadi Saeed
机构信息
Department of Radiology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
出版信息
J Clin Imaging Sci. 2012;2:85. doi: 10.4103/2156-7514.105269. Epub 2012 Dec 31.
OBJECTIVE
To assess the effect of injecting magnesium sulfate on Doppler parameters of fetal umbilical and middle cerebral arteries (MCA) in women with severe preeclampsia.
MATERIALS AND METHODS
A total of 21 patients with severe preeclampsia admitted to Imam Reza Hospital, Kermanshah (Iran), were evaluated. Before and after administration of magnesium sulfate, Doppler ultrasound scan was carried out to measure fetal middle cerebral artery and umbilical artery blood flow. Paired t-test was used for statistical analysis.
RESULTS
After injection of magnesium sulfate, the mean resistivity index (RI)-umbilical, and pulsatility index (PI)-cerebral showed a statistically significant reduction (P < 0.001). The cerebroumbilical C/U ratio increased after the intervention (P < 0.001). The PI-umbilical (P = 0.1) and pre- and post-RI-cerebral (P = 0.96) did not have statistically significant changes.
CONCLUSIONS
Infusion of magnesium sulfate significantly decreases the flow in the fetus RI-umbilical and PI-MCA, and it increases C/U ratio indices in color Doppler ultrasound.
目的
评估硫酸镁注射对重度子痫前期孕妇胎儿脐动脉和大脑中动脉（MCA）多普勒参数的影响。
材料与方法
对伊朗克尔曼沙赫伊玛目礼萨医院收治的21例重度子痫前期患者进行评估。在硫酸镁给药前后，进行多普勒超声扫描以测量胎儿大脑中动脉和脐动脉血流。采用配对t检验进行统计分析。
结果
注射硫酸镁后，平均脐动脉阻力指数（RI）和大脑中动脉搏动指数（PI）显示出统计学显著降低（P < 0.001）。干预后大脑 - 脐动脉C/U比值增加（P < 0.001）。脐动脉PI（P = 0.1）以及大脑中动脉RI给药前后（P = 0.96）无统计学显著变化。
结论
硫酸镁输注显著降低胎儿脐动脉RI和大脑中动脉PI血流，并增加彩色多普勒超声中的C/U比值指数。
Zotero 插件