Department of Chemical Engineering, Tsinghua University, Beijing 100084, PR China.
Chem Commun (Camb). 2013 Mar 18;49(22):2234-6. doi: 10.1039/c3cc38397k.
We have presented a self-cross-link strategy to fabricate HSA nanoparticles using a desolvation method. The nanoparticles were stabilized by intermolecular disulfide bonds while still dissolvable in reducing media. The fabrication process does not involve any toxic chemicals and hence the nanoparticles may be useful as a drug carrier.
我们提出了一种自交联策略，使用去溶剂化方法制备 HSA 纳米粒子。纳米粒子通过分子间二硫键稳定，同时仍可溶解于还原介质中。该制备过程不涉及任何有毒化学物质，因此这些纳米粒子可用作药物载体。
