人T淋巴细胞中白细胞介素-2撤除诱导凋亡的评估。
Evaluation of IL-2-withdrawal-induced apoptosis in human T lymphocytes.
作者信息
Oliveira Joao Bosco
机构信息
Pediatrics Department, Medical Institute Prof. Fernando Figueira-IMIP, Recife, PE, Brazil.
出版信息
Methods Mol Biol. 2013;979:25-31. doi: 10.1007/978-1-62703-290-2_3.
PMID:23397385
Abstract
Proper lymphocyte apoptosis is critical for the maintenance of immune system homeostasis, and evaluation of cell death is useful in a number of clinical and research settings. We describe here how to evaluate the integrity of the intrinsic pathway of lymphocyte apoptosis triggered by starvation for IL-2 or other survival cytokines.
摘要
适当的淋巴细胞凋亡对于维持免疫系统稳态至关重要，并且细胞死亡评估在许多临床和研究环境中都很有用。我们在此描述如何评估因白细胞介素-2或其他存活细胞因子缺乏而引发的淋巴细胞凋亡内在途径的完整性。
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