The vascular endothelium in diabetes and its potential as a therapeutic target.
作者信息
Liu Zhenqi
机构信息
Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville, VA 22908, USA.
出版信息
Rev Endocr Metab Disord. 2013 Mar;14(1):1-3. doi: 10.1007/s11154-013-9238-8.
Abstract
摘要
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本文引用的文献
1
Glucagon-like peptide 1 recruits microvasculature and increases glucose use in muscle via a nitric oxide-dependent mechanism.胰高血糖素样肽 1 通过一氧化氮依赖的机制募集微血管并增加肌肉中的葡萄糖利用。
Diabetes. 2012 Apr;61(4):888-96. doi: 10.2337/db11-1073. Epub 2012 Feb 22.
2
Angiotensin II receptors modulate muscle microvascular and metabolic responses to insulin in vivo.血管紧张素 II 受体调节体内胰岛素对肌肉微血管和代谢的反应。
Diabetes. 2011 Nov;60(11):2939-46. doi: 10.2337/db10-1691. Epub 2011 Sep 6.
3
Insulin regulates its own delivery to skeletal muscle by feed-forward actions on the vasculature.胰岛素通过对血管的前馈作用来调节自身向骨骼肌的输送。
Am J Physiol Endocrinol Metab. 2011 Aug;301(2):E252-63. doi: 10.1152/ajpendo.00186.2011. Epub 2011 May 24.
4
Infusing lipid raises plasma free fatty acids and induces insulin resistance in muscle microvasculature.输注脂质会提高血浆游离脂肪酸水平，并在肌肉微脉管系统中诱发胰岛素抵抗。
J Clin Endocrinol Metab. 2009 Sep;94(9):3543-9. doi: 10.1210/jc.2009-0027. Epub 2009 Jun 30.
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Insulin and insulin-like growth factor-I receptors differentially mediate insulin-stimulated adhesion molecule production by endothelial cells.胰岛素和胰岛素样生长因子-I受体以不同方式介导胰岛素刺激内皮细胞产生黏附分子。
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The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action.胰岛素的血管作用控制其向肌肉的输送，并调节骨骼肌胰岛素作用中的限速步骤。
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