Salkić Almir, Brkić Fuad, Cickusić Amra, Cickusić Elmir, Altumbabić Hasan
University Clinical Centre Tuzla, Department of ENT Surgery, Tuzla, Bosnia and Herzegovina.
Coll Antropol. 2012 Nov;36 Suppl 2:53-7.
Bosnia and Herzegovina (B&H) is one of the Eastern European countries with lacking data on thyroid cancer (TC) epidemiology. We aimed to assess the incidence of TC in Tuzla Canton of B&H during a 10-year period (1999-2008). We retrospectively evaluated 65000 hospital records of both inpatients and outpatients with possible thyroid symptoms residing in Tuzla Canton of B&H (total of 496280 inhabitants) between 1999 and 2008. Patients with histological proof of TC were included in study. Incidence rates were calculated with age standardisation using European standard population. Trends in incidence were evaluated as moving three-year averages. During observed period 117 patients met the diagnostic criteria for TC with male to female ratio of 1:4.85. Median age of all cases was 51 years (interquartile range: 41 to 60) with men in average 9 years older than women at the time of diagnosis. The mean annual standardized incidence was found to be 2.30/10(5) (% 95 CI = 1.38-3.22) inhabitants ranging from 1.0 to 3.2 per 10(5). The average crude incidence in men was 0.82/10(5) and 3.83/10(5) in women. The prevalence of TC, at the end of the observed period was found to be 23.58/10(5) (% 95 CI = 19.3-27.58). There is a slight decline of incidence in our region during the observed period, but with the increase in the latest years of the study. This increase is probably the result of combination of various factors, mainly the better detection of new cases due to wider availability of diagnostics. Based on depicted trends, we believe that in the future years, TC incidence in our region will continue to rise.
波斯尼亚和黑塞哥维那（波黑）是东欧缺乏甲状腺癌（TC）流行病学数据的国家之一。我们旨在评估1999年至2008年这10年间波黑图兹拉州TC的发病率。我们回顾性评估了1999年至2008年间居住在波黑图兹拉州（共496280名居民）有甲状腺相关症状的65000例住院患者和门诊患者的医院记录。有TC组织学证据的患者纳入研究。发病率采用欧洲标准人口进行年龄标准化计算。发病率趋势以三年移动平均值进行评估。在观察期内，117例患者符合TC诊断标准，男女比例为1:4.85。所有病例的中位年龄为51岁（四分位间距：41至60岁），诊断时男性平均比女性大9岁。年平均标准化发病率为2.30/10⁵（95%可信区间 = 1.38 - 3.22）居民，范围为每10⁵中有1.0至3.2例。男性的平均粗发病率为0.82/10⁵，女性为3.83/10⁵。在观察期末，TC患病率为23.58/10⁵（95%可信区间 = 19.3 - 27.58）。在观察期内，我们地区的发病率略有下降，但在研究的最后几年有所上升。这种上升可能是多种因素共同作用的结果，主要是由于诊断手段的广泛应用，新病例的检测得到了改善。基于所描述的趋势，我们认为在未来几年，我们地区的TC发病率将继续上升。
