Tosic Zoran, Salkic Nermin, Krizic Natasa, Djedovic Samed, Fijuljanin Mirela, Barakovic Devla
General Hospital Brcko, Brcko, Bosnia and Herzegovina.
Department of Gastroenterology and Hepatology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.
Med Arch. 2013;67(5):333-5. doi: 10.5455/medarh.2013.67.333-335.
there is no epidemiological estimation of the incidence and prevalence of CDin the adult population in Bosnia and Herzegovina(B&H), nor there are reports about the clinical presentation of CDin patients in B&H.
to assess the epidemiological and clinical characteristics of CDin the adult population in Tuzla Canton in northeast of Bosnia and Herzegovina.
we retrospectively analyzed all hospital records of both adult inpatients and outpatients evaluated in University Clinical Center Tuzla, with suspected CD and residing in Tuzla Canton of B&H between 1.1.2007 and 31.12.2009.
during the 3-year period we registered 42 cases of celiac disease (CD) with 31/42 (73.8%) of female and 11/42 (26.2%) of male patients - male to female ratio 1 to 2.82. The average annual crude incidence of CD during the observed period was 2.55/105 population (%95 CI=1.74-3.36). The average crude incidence in men was 1.51/105 and 4.08/105 in women. The average annual standardized incidence during the time period 2007-2009 was 1.89/105 (%95 CI=1.32-2.56). The sum prevalence during the study period was 7.66/105 population. Prevalence among men was 4.53/105 and 12.23/105 among women.
The incidence of CD in our region is demonstrating a steep rise and apparently low prevalence in our region is merely a result of poor availability of diagnostics in previous years.
波斯尼亚和黑塞哥维那（波黑）成年人群中，尚无关于乳糜泻（CD）发病率和患病率的流行病学评估，也没有关于波黑CD患者临床表现的报告。
评估波斯尼亚和黑塞哥维那东北部图兹拉州成年人群中CD的流行病学和临床特征。
我们回顾性分析了2007年1月1日至2009年12月31日期间在图兹拉大学临床中心接受评估的所有疑似CD的成年住院患者和门诊患者的医院记录，这些患者居住在波黑的图兹拉州。
在这3年期间，我们登记了42例乳糜泻（CD）病例，其中女性患者31/42（73.8%），男性患者11/42（26.2%），男女比例为1比2.82。观察期间CD的年平均粗发病率为2.55/10⁵人口（95%CI = 1.74 - 3.36）。男性的平均粗发病率为1.51/10⁵，女性为4.08/10⁵。2007 - 2009年期间的年平均标准化发病率为1.89/10⁵（95%CI = 1.32 - 2.56）。研究期间的总患病率为7.66/10⁵人口。男性患病率为4.53/10⁵，女性为12.23/10⁵。
我们地区CD的发病率呈急剧上升趋势，而该地区目前明显较低的患病率仅仅是前几年诊断手段缺乏的结果。
