Cowen D, Thomas L, Richaud P, Pierre F, Pigneux J
Service de Radiothérapie, Fondation Bergonié, Bordeaux.
Ann Otolaryngol Chir Cervicofac. 1990;107(2):121-5.
From 1970 to 1985, 299 patients with carcinoma of the lip were entirely managed at the Bergonié Foundation. Interstitial radiotherapy was most commonly used. It resulted in a successful local control in 96% of cases (238/248), while cosmetic and functional results seemed better than those of surgery. However, surgery seemed more performant for in situ carcinomas, late aggressive T3 carcinomas, local recurrences, as for T4 lesions associated with other techniques. After reviewing the case history of patients with local recurrences, we found technical faults in one half of those managed by interstitial radiotherapy. Local control rates after surgical salvage of recurrences was 99%. Treatment of neck nodes was not discussed in this publication.
1970年至1985年期间，299例唇癌患者在贝戈涅基金会接受了全面治疗。间质放疗是最常用的治疗方法。该方法在96%的病例（238/248）中实现了成功的局部控制，同时美容和功能效果似乎优于手术治疗。然而，手术对于原位癌、晚期侵袭性T3癌、局部复发以及与其他技术相关的T4病变似乎更有效。在回顾局部复发患者的病史后，我们发现接受间质放疗的患者中有一半存在技术失误。复发后手术挽救的局部控制率为99%。本出版物未讨论颈部淋巴结的治疗。
