Avian Virology & Immunology Unit, Veterinary and Agrochemical Research Centre, Groeselenberg, Brussels, Belgium.
Epidemiol Infect. 2013 Nov;141(11):2428-43. doi: 10.1017/S0950268813000125. Epub 2013 Feb 11.
In this study, shedding and transmission of three H5/H7 low pathogenic avian influenza viruses (LPAIVs) in poultry was characterized and the impact of floor system on transmission was assessed. Transmission experiments were simultaneously conducted with two groups of animals housed on either a grid or a floor covered with litter. Transmission was observed for H5N2 A/Ch/Belgium/150VB/99 LPAIV. This virus was shed almost exclusively via the oropharynx and no impact of floor system was seen. Transmission was also seen for H7N1 A/Ch/Italy/1067/v99 LPAIV, which was shed via both the oropharynx and cloaca. A slight increase in transmission was seen for animals housed on litter. H5N3 A/Anas Platyrhynchos/Belgium/09-884/2008 LPAIV did not spread to susceptible animals, regardless of the floor system. This study shows that environmental factors such as floor systems used in poultry barns may act upon the transmission of LPAIVs. However, the level of influence depends on the virus under consideration and, more specifically, its principal replication sites.
在这项研究中，对三种 H5/H7 低致病性禽流感病毒（LPAIV）在禽类中的脱落和传播进行了研究，并评估了地面系统对传播的影响。将两组动物分别饲养在网格或覆盖垫料的地面上，同时进行了传播实验。对 H5N2 A/Ch/Belgium/150VB/99 LPAIV 进行了观察。该病毒几乎仅通过口咽部分泌，地面系统无影响。H7N1 A/Ch/Italy/1067/v99 LPAIV 也可通过口咽和泄殖腔进行传播，在垫料上饲养的动物中，传播略有增加。H5N3 A/Anas Platyrhynchos/Belgium/09-884/2008 LPAIV 无论使用哪种地面系统，均未传播至易感动物。本研究表明，禽舍中使用的环境因素（如地面系统）可能会影响 LPAIV 的传播。然而，影响程度取决于所研究的病毒，更具体地说，取决于其主要复制部位。
