Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, PR China.
Carbohydr Polym. 2013 Feb 15;92(2):1432-42. doi: 10.1016/j.carbpol.2012.10.071. Epub 2012 Nov 16.
Bacterial cellulose (BC, also known as microbial cellulose, MC) is a promising natural polymer which is biosynthesized by certain bacteria. This review focused on BC-based materials which can be utilized for skin tissue repair. Firstly, it is illustrated that BC has unique structural and mechanical properties as compared with higher plant cellulose, and is thus expected to become a commodity material. Secondly, we summarized the basic properties and different types of BC, including self-assembled, oriented BC, and multiform BC. Thirdly, composites prepared by using BC in conjunction with other polymers are explored, and the research on BC for application in skin tissue engineering is addressed. Finally, experimental results and clinical treatments assessing the performance of wound healing materials based on BC were examined. With its superior mechanical properties, as well as its excellent biocompatibility, BC was shown to have great potential for biomedical application and very high clinical value for skin tissue repair.
细菌纤维素（BC，也称为微生物纤维素，MC）是一种有前途的天然聚合物，由某些细菌生物合成。本综述主要关注可用于皮肤组织修复的基于 BC 的材料。首先，与高等植物纤维素相比，BC 具有独特的结构和机械性能，因此有望成为一种商品材料。其次，我们总结了 BC 的基本性质和不同类型，包括自组装、定向 BC 和多形态 BC。第三，探索了通过将 BC 与其他聚合物结合制备的复合材料，并研究了 BC 在皮肤组织工程中的应用。最后，检查了基于 BC 的伤口愈合材料的性能的实验结果和临床治疗。BC 具有优异的机械性能和良好的生物相容性，在生物医学应用方面具有巨大的潜力，对皮肤组织修复具有非常高的临床价值。
