Salminen U S, Halttunen P, Taskinen E, Mattila S
Department of Thoracic and Cardiovascular Surgery, Helsinki University Central Hospital, Finland.
Ann Thorac Surg. 1990 May;49(5):830-2. doi: 10.1016/0003-4975(90)90039-9.
An endotracheal chondroma with recurrent course and malignant transformation is described. The first chondroma recurrence appeared 5 years after the primary operation, with no histopathological signs of malignancy. A second recurrence after a further 6 years showed obvious histological evidence of malignant chondrosarcoma. A third recurrence after 1 more year metastasized to various organs and led to the patient's death 14 years from the date of primary diagnosis.
本文描述了一例具有复发病程并发生恶性转化的气管内软骨瘤。首次软骨瘤复发发生在初次手术后5年，无恶性组织病理学迹象。再过6年后的第二次复发显示出明显的恶性软骨肉瘤组织学证据。又过1年后的第三次复发转移至多个器官，并导致患者自初次诊断之日起14年后死亡。
