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一例偶然发现的原发性气管软骨肉瘤成功手术治疗的病例报告及文献见解

A case report and literature insights of the successful surgical management of an incidentally detected primary tracheal Chondrosarcoma.

作者信息

Al Laham Omar, Al Natour Omar, Ibrahim Basha Zein, Ahmad Raneem, Al Kateb Kamal

机构信息

Department of Vascular Surgery, Klinikum Herford, Kreiskliniken Herford-Bünde AöR, Herford, Germany.

Department of General and Visceral Surgery, Thoracic Surgery and Proctology, Ruhr University Bochum, Klinikum Herford, Kreiskliniken Herford-Bünde AöR, Herford, Germany.

出版信息

Int J Surg Case Rep. 2025 Sep;134:111716. doi: 10.1016/j.ijscr.2025.111716. Epub 2025 Jul 23.

Abstract

INTRODUCTION AND IMPORTANCE

Primary tracheal neoplasia constitute a rare class of oncological entities. They constitute merely 0.1 % of all subsets of malignancies. They are observed more in males than females. Furthermore, they are generally diagnosed after the age of 65 years due to their mostly asymptomatic disease progression. Despite being predominantly asymptomatic, symptoms manifest typically after a 75 % tracheal lumen obstruction.

CASE PRESENTATION

In this case report, we demonstrate the rare case of a 59-year-old Middle Eastern male who presented to the Thoracic Surgery clinic complaining only of a progressive dyspnea. The conducted preoperative diagnostic examinations included a computed tomography scan and a bronchoscopy with biopsy. They paved the path to establishing a preliminary diagnosis. Due to the constellation of clinical and radiological findings, a surgical intervention was indicated.

CLINICAL DISCUSSION

Curative treatment was accomplished via tracheal segmental resection and carrying out a primary end-to-end anastomosis. The postoperative course was unremarkable and the patient was postoperatively followed-up in the Thoracic Surgery outpatient clinic for 1 year. To this day, there is no evidence of tumor recurrence or remanence.

CONCLUSION

Tracheal chondrosarcoma is an extremely rare tumor. After conducting a meticulous literature review, we observed that our case is only the 36th documented worldwide and the first reported in Syria. It highlights the importance of considering this diagnosis in clinical practice and advocates for further research to improve diagnostic methods, surgical techniques, and follow-up protocols to better manage such rare conditions.

摘要

引言与重要性

原发性气管肿瘤是一类罕见的肿瘤实体。它们仅占所有恶性肿瘤亚型的0.1%。男性比女性更易观察到此类肿瘤。此外,由于其疾病进展大多无症状,通常在65岁以后才被诊断出来。尽管主要无症状,但症状通常在气管腔阻塞75%后才出现。

病例介绍

在本病例报告中,我们展示了一例罕见病例,一名59岁的中东男性因进行性呼吸困难就诊于胸外科门诊。术前进行的诊断检查包括计算机断层扫描和支气管镜活检。这些检查为初步诊断铺平了道路。由于临床和影像学检查结果的综合判断,需要进行手术干预。

临床讨论

通过气管节段切除和一期端端吻合完成了根治性治疗。术后过程顺利,患者在胸外科门诊接受了1年的术后随访。至今,没有肿瘤复发或残留的证据。

结论

气管软骨肉瘤是一种极其罕见的肿瘤。在进行了细致的文献回顾后,我们发现我们的病例是全球第36例有记录的病例,也是叙利亚首例报告病例。它强调了在临床实践中考虑这一诊断的重要性,并提倡进一步研究以改进诊断方法、手术技术和随访方案,从而更好地管理此类罕见疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7075/12309486/8be335163c1a/gr1.jpg

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