Rothe T
Innere Medizin & Pneumologie, Zürcher Höhenklinik Davos, Klinikstrasse 6, 7272 Davos Clavadel.
Praxis (Bern 1994). 2013 Feb 13;102(4):211-8. doi: 10.1024/1661-8157/a001189.
Asthma is not a homogenous disease but a bundle of different phenotypes producing common symptoms due to swelling of bronchial mucosa and constriction of the airway smooth muscle. Beyond the treatment with a combination of topical steroids and long-acting beta agonists, new therapeutic options arise with the knowledge of different phenotypes. One option, specifically in allergic asthma, is the long known allergen immunotherapy. To identify the individual phenotype a diagnostic work up is warranted when the asthma is diagnosed and whenever asthma control cannot be maintained.
哮喘并非一种单一的疾病,而是一系列不同的表型,由于支气管黏膜肿胀和气道平滑肌收缩而产生共同症状。除了局部类固醇和长效β受体激动剂联合治疗外,随着对不同表型的了解,出现了新的治疗选择。一种选择,特别是在过敏性哮喘中,是早已为人所知的过敏原免疫疗法。当诊断出哮喘以及无法维持哮喘控制时,为了确定个体表型,有必要进行诊断性检查。