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Probing arginine side-chains and their dynamics with carbon-detected NMR spectroscopy: application to the 42 kDa human histone deacetylase 8 at high pH.

作者信息

Werbeck Nicolas D, Kirkpatrick John, Hansen D Flemming

机构信息

Institute of Structural and Molecular Biology, University College London, Gower Street, WC1E 6BT, London, UK.

出版信息

Angew Chem Int Ed Engl. 2013 Mar 11;52(11):3145-7. doi: 10.1002/anie.201209385. Epub 2013 Feb 10.

DOI:10.1002/anie.201209385
PMID:23401322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4016738/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2198/4016738/c98f34c21315/anie0052-3145-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2198/4016738/307aa71f972d/anie0052-3145-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2198/4016738/b9d83ca658bd/anie0052-3145-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2198/4016738/c98f34c21315/anie0052-3145-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2198/4016738/307aa71f972d/anie0052-3145-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2198/4016738/b9d83ca658bd/anie0052-3145-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2198/4016738/c98f34c21315/anie0052-3145-f3.jpg

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本文引用的文献

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Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):18954-9. doi: 10.1073/pnas.1104808108. Epub 2011 Nov 11.
2
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Bioorg Med Chem Lett. 2011 Apr 1;21(7):2129-32. doi: 10.1016/j.bmcl.2011.01.128. Epub 2011 Feb 2.
3
Activation and inhibition of histone deacetylase 8 by monovalent cations.
使用分子动力学模拟解析蛋白质骨架 NH 和侧链甲基基团的动态。
J Chem Theory Comput. 2024 Jul 23;20(14):6316-6327. doi: 10.1021/acs.jctc.4c00378. Epub 2024 Jul 3.
4
Observation of Arginine Side-Chain Motions Coupled to the Global Conformational Exchange Process in Deubiquitinase A.去泛素化酶A中与全局构象交换过程耦合的精氨酸侧链运动观察
ACS Omega. 2022 Mar 8;7(11):9936-9943. doi: 10.1021/acsomega.2c00492. eCollection 2022 Mar 22.
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C Direct Detected NMR for Challenging Systems.C 直接检测 NMR 用于具有挑战性的体系。
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