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胃类癌与肥胖:关联还是巧合?两例报告及文献综述

Gastric carcinoid and obesity: association or coincidence? Report of two cases and literature review.

作者信息

Al-Harbi Obaid, Shakir Mustafa, Al-Brahim Nabeel

机构信息

Department of Surgery, Farwaniya Hospital, 81004 Sabah Al-Naser, Kuwait.

出版信息

Case Rep Gastrointest Med. 2013;2013:848075. doi: 10.1155/2013/848075. Epub 2013 Jan 15.

DOI:10.1155/2013/848075
PMID:23401809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3562567/
Abstract

Bariatric surgery is a prevalent procedure due to the high incidence of obesity and comorbidities. Upper gastrointestinal endoscopy is one of the procedures used to evaluate the patient before surgery. However, its role is questionable. The incidental findings during endoscopy are variable including inflammatory diseases, and ulcers, and epithelial and stromal tumors. Herein a report of two obese sisters with incidental gastric carcinoids was diagnosed in prebariatric surgery endoscopy. Case Summary. 35- and 41-year-old female patients presented with obesity and BMI of 102 and 46 kg/m(2), respectively. Both patients underwent upper gastrointestinal endoscopy as part of presurgical evaluation. Multiple polyps were indentified in both patients, and biopsy was taken. Histological examination revealed tumors that were formed by nests of epithelial cells. The cells have eosinophilic cytoplasm and monomorphic nuclei, typical morphology of neuroendocrine tumors. Conclusions. (1) Upper gastrointestinal endoscopy is an important procedure for prebariatric surgery evaluation. (2) Gastric carcinoid is a rare tumor with higher incidence among obese patients.

摘要

由于肥胖症及合并症的高发病率,减肥手术是一种常见的手术。上消化道内镜检查是术前评估患者时使用的程序之一。然而,其作用存在疑问。内镜检查时的偶然发现多种多样,包括炎症性疾病、溃疡以及上皮和间质肿瘤。本文报告了两例肥胖姐妹,她们在减肥手术前的内镜检查中被诊断出偶然患有胃类癌。病例摘要。两名女性患者,年龄分别为35岁和41岁,均患有肥胖症,体重指数分别为102和46kg/m²。两名患者均接受了上消化道内镜检查作为术前评估的一部分。两名患者均发现有多个息肉,并进行了活检。组织学检查显示肿瘤由上皮细胞巢组成。细胞具有嗜酸性细胞质和单形核,这是神经内分泌肿瘤的典型形态。结论。(1)上消化道内镜检查是减肥手术术前评估的重要程序。(2)胃类癌是一种罕见肿瘤,在肥胖患者中的发病率较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac9/3562567/b52a822d180c/CRIM.GM2013-848075.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac9/3562567/272347c06423/CRIM.GM2013-848075.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac9/3562567/b52a822d180c/CRIM.GM2013-848075.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac9/3562567/272347c06423/CRIM.GM2013-848075.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac9/3562567/b52a822d180c/CRIM.GM2013-848075.002.jpg

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