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[门静脉高压肿瘤发生患者的内镜止血]

[Endoscopic hemostasis in patients with portal hypertension tumor genesis].

作者信息

Khubutia M Sh, Pinchuk T P, Sogreshilin S S, Bugaev S A, Lutsyk K N, Chugunov A O

出版信息

Eksp Klin Gastroenterol. 2012(6):53-7.

Abstract

AIM OF THE STUDY

to assess the results of using endoscopic techniques to achieve hemostasis for the control of bleeding and the prevention of recurrent bleeding from esophageal and gastric varices in the patients with primary liver cancer and metastatic liver lesions.

MATERIALS AND METHODS

in the period of 2009-2011,7 patients with primary liver cancer or metastatic liver lesions complicated by gastro-esophageal bleeding were treated in the Sklifosovsky Clinical and Research Institute for Emergency Medicine. The sources of bleeding were esophageal varices in 6 patients, gastric varices in 1.

RESULTS

a diagnostic esophagogastroduodenoscopy (EGDS) revealed, besides the varices, an erosive hemorrhagic gastritis in 4 patients, a ruptured mucosa of cardio-esophageal transition in 1, an erosive hemorrhagic gastritis and a liver tumour invasion in the stomach antrum in 1. The hemostasis achieved by means of paravasal injections with a 20% glucose solution was efficient in 2 of 3 patients. The endoscopic ligations of esophageal varices were performed in 3 patients. Five patients died from the underlying disease progressing. In one of them, the cause of death was a recurrent bleeding from esophageal varices.

CONCLUSIONS

in the patients with primary liver cancer and metastatic liver lesions, the use of mini-invasive endoscopic techniques is more appropriate, because the surgical treatment of this patient population carries a very high risk.

摘要

研究目的

评估采用内镜技术实现止血以控制出血,并预防原发性肝癌和肝转移瘤患者食管和胃静脉曲张再出血的效果。

材料与方法

2009年至2011年期间,斯克利福索夫斯基急诊医学临床与研究所对7例原发性肝癌或肝转移瘤合并胃食管出血的患者进行了治疗。出血来源为6例食管静脉曲张,1例胃静脉曲张。

结果

诊断性食管胃十二指肠镜检查(EGDS)显示,除静脉曲张外,4例患者存在糜烂性出血性胃炎,1例食管贲门交界处黏膜破裂,1例同时存在糜烂性出血性胃炎和胃窦部肝肿瘤侵犯。3例患者中2例通过旁静脉注射20%葡萄糖溶液实现止血有效。3例患者进行了食管静脉曲张内镜结扎术。5例患者死于基础疾病进展。其中1例死亡原因是食管静脉曲张再出血。

结论

对于原发性肝癌和肝转移瘤患者,采用微创内镜技术更为合适,因为该患者群体的手术治疗风险非常高。

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