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欧洲自我报告的食物过敏的卫生部门成本:一项基于患者的疾病成本研究。

Health sector costs of self-reported food allergy in Europe: a patient-based cost of illness study.

作者信息

Fox Margaret, Mugford Miranda, Voordouw Jantine, Cornelisse-Vermaat Judith, Antonides Gerrit, de la Hoz Caballer Belen, Cerecedo Inma, Zamora Javier, Rokicka Ewa, Jewczak Maciej, Clark Allan B, Kowalski Marek L, Papadopoulos Nikos, Knulst Anna C, Seneviratne Suranjith, Belohlavkova Simona, Asero Roberto, de Blay Frederic, Purohit Ashok, Clausen Michael, Flokstra de Blok Bertine, Dubois Anthony E, Fernandez-Rivas Montserrat, Burney Peter, Frewer Lynn J, Mills Clare E N

机构信息

1 School of Allied Health Professions, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK.

出版信息

Eur J Public Health. 2013 Oct;23(5):757-62. doi: 10.1093/eurpub/ckt010. Epub 2013 Feb 11.

Abstract

INTRODUCTION

Food allergy is a recognized health problem, but little has been reported on its cost for health services. The EuroPrevall project was a European study investigating the patterns, prevalence and socio-economic cost of food allergy.

AIMS

To investigate the health service cost for food-allergic Europeans and the relationship between severity and cost of illness.

METHODS

Participants recruited through EuroPrevall studies in a case-control study in four countries, and cases only in five countries, completed a validated economics questionnaire. Individuals with possible food allergy were identified by clinical history, and those with food-specific immunoglobulin E were defined as having probable allergy. Data on resource use were used to estimate total health care costs of illness. Mean costs were compared in the case-control cohorts. Regression analysis was conducted on cases from all 9 countries to assess impact of country, severity and age group.

RESULTS

Food-allergic individuals had higher health care costs than controls. The mean annual cost of health care was international dollars (I$)2016 for food-allergic adults and I$1089 for controls, a difference of I$927 (95% confidence interval I$324-I$1530). A similar result was found for adults in each country, and for children, and was not sensitive to baseline demographic differences. Cost was significantly related to severity of illness in cases in nine countries.

CONCLUSIONS

Food allergy is associated with higher health care costs. Severity of allergic symptoms is a key explanatory factor.

摘要

引言

食物过敏是一个公认的健康问题,但关于其对卫生服务成本的影响报道较少。欧洲食物过敏患病率及成本研究项目(EuroPrevall)是一项欧洲研究,旨在调查食物过敏的模式、患病率及社会经济成本。

目的

调查欧洲食物过敏患者的卫生服务成本以及疾病严重程度与成本之间的关系。

方法

通过EuroPrevall研究在四个国家招募参与者进行病例对照研究,并在五个国家仅招募病例,参与者完成一份经过验证的经济学问卷。根据临床病史确定可能患有食物过敏的个体,那些具有食物特异性免疫球蛋白E的个体被定义为可能患有过敏。利用资源使用数据估算疾病的总医疗保健成本。对病例对照队列中的平均成本进行比较。对来自所有9个国家的病例进行回归分析,以评估国家、严重程度和年龄组的影响。

结果

食物过敏个体的医疗保健成本高于对照组。食物过敏成人的年平均医疗保健成本为2016国际美元(I$),对照组为1089国际美元,相差927国际美元(95%置信区间为324国际美元至1530国际美元)。在每个国家的成年人以及儿童中都发现了类似的结果,并且对基线人口统计学差异不敏感。在九个国家的病例中,成本与疾病严重程度显著相关。

结论

食物过敏与更高的医疗保健成本相关。过敏症状的严重程度是一个关键的解释因素。

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