School of Technology and Business Studies, Computer Engineering, Dalarna University, Borlänge, Sweden.
Parkinsonism Relat Disord. 2013 May;19(5):553-6. doi: 10.1016/j.parkreldis.2013.01.011. Epub 2013 Feb 9.
The purpose of this study was to examine repeated measures of fine motor function in relation to self-assessed motor conditions in Parkinson's disease (PD).
One-hundred PD patients, 65 with advanced PD and 35 patients with different disease stages have utilized a test battery in a telemedicine setting. On each test occasion, they initially self-assessed their motor condition (from 'very off' to 'very dyskinetic') and then performed a set of fine motor tests (tapping and spiral drawings).
The motor tests scores were found to be the best during self-rated On. Self-rated dyskinesias caused more impaired spiral drawing performance (mean = 9.8% worse, P < 0.001) but at the same time tapping speed was faster (mean = 5.0% increase, P < 0.001), compared to scores in self-rated Off.
The fine motor tests of the test battery capture different symptoms; the spiral impairment primarily relates to dyskinesias whereas the tapping speed captures the Off symptoms.
本研究旨在探讨帕金森病(PD)患者的精细运动功能与自我评估运动状况的重复测量之间的关系。
100 名 PD 患者,65 名晚期 PD 患者和 35 名不同疾病阶段的患者在远程医疗环境中使用了一组测试。在每次测试中,他们首先自我评估自己的运动状况(从“非常差”到“非常运动障碍”),然后进行一系列精细运动测试(敲击和螺旋绘图)。
自我评估的 On 期间发现运动测试的得分最佳。自我评估的运动障碍导致螺旋绘图表现更差(平均差 9.8%,P<0.001),但同时敲击速度更快(平均增加 5.0%,P<0.001),与自我评估的 Off 时相比。
测试组合的精细运动测试捕捉到不同的症状;螺旋损伤主要与运动障碍有关,而敲击速度则捕捉到 Off 症状。