Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA.
Obes Surg. 2013 May;23(5):663-8. doi: 10.1007/s11695-012-0854-2.
The contribution of obesity to the thromboembolic risks of surgery suggests that patients undergoing bariatric surgery would have a particularly high risk of postoperative pulmonary embolism (PE) and/or deep venous thrombosis (DVT). This study aimed to assess the prevalence of in-hospital PE, DVT, and venous thromboembolism (VTE) following bariatric surgery in the USA from 2007 to 2009.
We used the database of the Nationwide Inpatient Sample.
The prevalence of PE was 4,500 of 508,230 (0.9 %). The prevalence of DVT not accompanied by PE was 6,480 of 508,230 (1.3 %) and VTE (either PE or DVT) occurred in 10,980 of 508,230 (2.2 %). In-hospital death among patients with PE was 130 of 508,231 (0.03 %). Vena cava filters were inserted in 1,515 of 508,230 (0.3 %) patients who underwent bariatric surgery. Among patients who had VTE, filters were inserted in 1,150 of 10,980 (10.5 %). Among patients who had neither PE nor DVT, prophylactic vena cava filters were inserted in 365 of 497,250 (0.07 %). Among patients with PE, in-hospital mortality was 25 of 635 (3.9 %) with a filter compared with 105 of 3,865 (2.7 %) (NS) without a filter. However, among patients with DVT alone, in-hospital mortality was 0 of 510 (0 %) with a filter compared with 80 of 5,970 (1.3 %) (P = 0.009) without a filter.
This investigation establishes a baseline for the incidence of venous thromboembolic complications following bariatric surgery in recent years. Determination of the present in-hospital rate of PE and DVT may contribute to antithrombotic prophylactic considerations.
肥胖对手术血栓栓塞风险的影响表明,接受减肥手术的患者术后发生肺栓塞(PE)和/或深静脉血栓形成(DVT)的风险特别高。本研究旨在评估 2007 年至 2009 年美国减肥手术后住院期间 PE、DVT 和静脉血栓栓塞症(VTE)的发生率。
我们使用了全国住院患者样本数据库。
PE 的发生率为 508230 例中的 4500 例(0.9%)。未伴有 PE 的 DVT 的发生率为 508230 例中的 6480 例(1.3%),VTE(PE 或 DVT)发生在 508230 例中的 10980 例(2.2%)。PE 患者的住院期间死亡率为 508231 例中的 130 例(0.03%)。在接受减肥手术的 508230 例患者中,有 1515 例(0.3%)插入了腔静脉滤器。在发生 VTE 的患者中,有 10980 例中的 1150 例(10.5%)插入了滤器。在既没有 PE 也没有 DVT 的患者中,在 497250 例中的 365 例(0.07%)预防性插入了腔静脉滤器。在有 PE 的患者中,有滤器的患者住院期间死亡率为 635 例中的 25 例(2.9%),而无滤器的患者为 3865 例中的 105 例(2.7%)(无统计学差异)。然而,在单独发生 DVT 的患者中,有滤器的患者住院期间死亡率为 510 例中的 0 例(0%),而无滤器的患者为 5970 例中的 80 例(1.3%)(P=0.009)。
本研究建立了近年来减肥手术后静脉血栓栓塞并发症发生率的基线。确定目前住院期间 PE 和 DVT 的发生率可能有助于抗血栓预防措施的考虑。