Department for General Psychology and Methodology, University of Bamberg, Markusplatz 3, 96047 Bamberg, Germany.
Brain. 2013 Mar;136(Pt 3):751-60. doi: 10.1093/brain/awt003. Epub 2013 Feb 11.
In visual search, the detection of pop-out targets is facilitated when the target-defining dimension remains the same compared with when it changes across trials. We tested the brain regions necessary for these dimensional carry-over effects using a voxel-based morphometry study with brain-lesioned patients. Participants had to search for targets defined by either their colour (red or blue) or orientation (right- or left-tilted), and the target dimension either stayed the same or changed on consecutive trials. Twenty-five patients were categorized according to whether they showed an effect of dimensional change on search or not. The two groups did not differ with regard to their performance on several working memory tasks, and the dimensional carry-over effects were not correlated with working memory performance. With spatial, sustained attention and working memory deficits as well as lesion volume controlled, damage within the right inferior parietal lobule (the angular and supramarginal gyri) extending into the intraparietal sulcus was associated with an absence of dimensional carry-over (P < 0.001, cluster-level corrected for multiple comparisons). The data suggest that these regions of parietal cortex are necessary to implement attention shifting in the context of visual dimensional change.
在视觉搜索中，当目标定义维度在试验中保持不变时，目标的检测会更加容易。我们使用基于体素的形态测量学研究对大脑受损的患者进行了测试，以研究实现这些维度延续效应所需的大脑区域。参与者必须根据颜色（红色或蓝色）或方向（向右或向左倾斜）来搜索目标，并且目标维度在连续试验中保持不变或发生变化。根据他们在搜索中是否表现出维度变化的效果，将 25 名患者分为两组。这两组在执行多项工作记忆任务的表现上没有差异，并且维度延续效应与工作记忆表现无关。在控制空间、持续注意力和工作记忆缺陷以及病变体积的情况下，损伤延伸到顶内沟的右下顶叶（角回和缘上回）与维度延续的缺失有关（P<0.001，簇水平多重比较校正）。这些数据表明，顶叶皮层的这些区域对于在视觉维度变化的情况下实施注意力转移是必要的。
