Riva M A, Madotto F, Conti S, Fornari C, Patronella G, Sormani M, D'Orso M I, De Vito G, Latocca R, Cesana G
Unità Medicina Occupazionale ed Ambientale, Azienda Ospedaliera San Gerardo di Monza via Pergolesi 33, 20900 Monza, Italy.
G Ital Med Lav Ergon. 2012 Jul-Sep;34(3 Suppl):283-5.
This study assessed the immunisation status against hepatitis B in healthcare students and residents, before their hospital internship, as suggested by the "National Immunization Prevention Plan 2012-2014". The concentration of antibodies against hepatitis B was measured in 2,491 subjects (70.90% women), born between 1980 and 1993 and visited between January 1st 2000 and July 15th 2012. Personal and serologic data were collected for each subjects. Individuals with antibody less than 10 mIU/mL (327, 13.3%) were given a booster dose and re-tested 2 months later. The multivariate logistic regression evidenced that immunization is influenced by the gender, the age at first vaccination, the time elapsed between first vaccination and antibody measurement. This study confirms the importance of measuring the concentration of antibodies against hepatitis B among healthcare students, even if they have previously been vaccinated, according to the "National Immunization Prevention Plan 2012-2014".
根据《2012 - 2014年国家免疫预防计划》的建议，本研究评估了医学生和住院医师在医院实习前的乙肝免疫状况。对2491名受试者（70.90%为女性）进行了乙肝抗体浓度检测，这些受试者出生于1980年至1993年之间，于2000年1月1日至2012年7月15日期间接受检查。收集了每个受试者的个人和血清学数据。抗体低于10 mIU/mL的个体（327人，占13.3%）接种了加强针，并在2个月后重新检测。多因素逻辑回归表明，免疫接种受性别、首次接种年龄、首次接种与抗体检测之间的时间间隔影响。本研究证实，根据《2012 - 2014年国家免疫预防计划》，即使医学生之前已接种疫苗，检测其乙肝抗体浓度也很重要。
