Sernia Sabina, Ortis Marina, Antoniozzi Tranquillo, Maffongelli Emanuele, La Torre Giuseppe
Center of Occupational Medicine, Sapienza University of Rome, 5-00185 Rome, Italy ; Department of Public Health and Infectious Diseases, Sapienza University of Rome, 5-00185 Rome, Italy.
Center of Occupational Medicine, Sapienza University of Rome, 5-00185 Rome, Italy.
Biomed Res Int. 2015;2015:712020. doi: 10.1155/2015/712020. Epub 2015 Jan 5.
Prophylaxis against hepatitis B virus (HBV) addressed to students of the faculties of health professions has received great attention. Objectives. The present study aims to assess vaccination coverage against hepatitis B in healthcare professionals in training.
A retrospective study was carried out using data from the students of medicine, dentistry, and health professions.
4180 vaccination certifications were examined through the internal database. Significant differences (<0.0001) emerge between the number of doses applied and the antibody level. 50.4% of the students have nonprotective antibody levels (<10 IU). The age of the first dose significantly influences the level of coverage, resulting in more coverage in those vaccinated with earlier onset (1-10 years). Antibody levels are not significantly different by type of course; the levels of noncoverage are present in 44.4% of the students of medicine and dentistry and in 50.6% among those belonging to the health professions.
This study represents one of the first experiences in Italy on vaccination against HBV and the relationship between doses of vaccination and antibody titer in the biomedical students that can configure a step forward in the real-time monitoring in order to establish a register of vaccination.
针对卫生专业院校学生的乙型肝炎病毒（HBV）预防措施受到了广泛关注。目的。本研究旨在评估接受培训的医护人员的乙肝疫苗接种覆盖率。
利用医学、牙科和卫生专业学生的数据进行了一项回顾性研究。
通过内部数据库检查了4180份疫苗接种证明。接种剂量与抗体水平之间存在显著差异（<0.0001）。50.4%的学生抗体水平无保护作用（<10 IU）。首剂接种年龄对覆盖率有显著影响，早期接种（1 - 10岁）的学生覆盖率更高。不同课程类型的抗体水平无显著差异；医学和牙科专业学生中44.4%未达到覆盖水平，卫生专业学生中这一比例为50.6%。
本研究是意大利首次针对生物医学专业学生进行乙肝疫苗接种以及接种剂量与抗体滴度关系的研究之一，可为建立疫苗接种登记册的实时监测向前迈出一步。
