Fuster V
Cardiovascular Institute, Mount Sinai Medical Center, New York, New York 10029-6574, USA.
Am J Cardiol. 1995 Sep 28;76(9):24C-33C. doi: 10.1016/s0002-9149(99)80467-6.
The basic mechanisms of atherosclerotic progression have been well elucidated during the last few years. In this brief presentation on the acute coronary syndromes, the fate of plaque rupture and our understanding of "passive" versus "active" rupture are defined. In addition to the phenomenon of plaque rupture, the thrombogenicity of atherosclerotic plaques in the genesis of coronary syndromes is defined. The combination of plaque disruption and high thrombogenic risk profile--including local and systemic factors--is vital to understanding the genesis of the acute coronary syndromes.
在过去几年中，动脉粥样硬化进展的基本机制已得到充分阐明。在本次关于急性冠脉综合征的简短报告中，定义了斑块破裂的转归以及我们对“被动”与“主动”破裂的理解。除了斑块破裂现象外，还定义了冠状动脉综合征发生过程中动脉粥样硬化斑块的血栓形成倾向。斑块破裂与高血栓形成风险特征（包括局部和全身因素）的结合对于理解急性冠脉综合征的发生至关重要。
