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开放性与腹腔镜下根治性膀胱前列腺切除术联合原位新膀胱术的评估:单术者经验

Evaluation of open and laparoscopic radical cystoprostatectomy combined with orthotopic neobladder: a single-surgeon experience.

作者信息

Akin Yigit, Celik Orcun, Ates Mutlu, Nuhoglu Baris, Erdogru Tibet

机构信息

Department of Urology, Erzincan University School of Medicine, Erzincan, Turkey.

出版信息

Urol Int. 2013;90(3):348-53. doi: 10.1159/000346755. Epub 2013 Feb 8.

Abstract

AIM

To compare the outcomes of laparoscopic (LRCP) and open radical cystoprostatectomy (ORCP) with orthotopic urinary diversion for muscle-invasive organ-confined bladder cancer by a single surgeon.

PATIENTS AND METHODS

Prospectively documented 15 LRCP and 15 ORCP patients, followed for at least 3 years, were included in our study. The demographic parameters of patients, preoperative radiologic staging, previous operations, surgical outcomes, complications, oncologic results and intermediate-term follow-up, postoperative chemotherapy and follow-up periods were recorded and evaluated.

RESULTS

The mean oncologic follow-up was 3 years. Transfusion rate, estimated blood loss, oral intake and narcotic analgesic requirement were statistically less in the LRCP group (p < 0.05). However, operation time and hospital stay were similar in both groups. The complication rates were not significantly different between the two groups. The mean number of dissected lymph nodes was 20.0 ± 1.7 in the ORCP and 22.6 ± 2.0 in the LRCP group. One patient in each group had a margin positive for bladder cancer.

CONCLUSIONS

The laparoscopic approach may be feasible for muscle-invasive organ-confined bladder cancer. Furthermore, LRCP provides less blood loss, early oral intake and postoperative pain management. Additionally, continence and sexual function may be provided by LRCP as with ORCP.

摘要

目的

由单一外科医生比较腹腔镜根治性膀胱前列腺切除术(LRCP)和开放性根治性膀胱前列腺切除术(ORCP)联合原位尿流改道术治疗肌层浸润性局限于器官的膀胱癌的疗效。

患者与方法

前瞻性记录的15例LRCP患者和15例ORCP患者纳入我们的研究,随访至少3年。记录并评估患者的人口统计学参数、术前放射学分期、既往手术史、手术结果、并发症、肿瘤学结果和中期随访、术后化疗及随访时间。

结果

平均肿瘤学随访时间为3年。LRCP组的输血率、估计失血量、口服摄入量和麻醉性镇痛药需求量在统计学上较少(p<0.05)。然而,两组的手术时间和住院时间相似。两组的并发症发生率无显著差异。ORCP组平均清扫淋巴结数为20.0±1.7个,LRCP组为22.6±2.0个。每组各有1例患者膀胱癌切缘阳性。

结论

腹腔镜手术方法对于肌层浸润性局限于器官的膀胱癌可能是可行的。此外,LRCP术中失血更少,术后能更早经口进食并进行疼痛管理。另外,与ORCP一样,LRCP也可保留控尿和性功能。

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