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多形红斑为不完全川崎病的首发表现。

Erythema multiforme as first sign of incomplete Kawasaki disease.

机构信息

Pediatric Unit, Maternal & Infant Department, S. Chiara University-Hospital, Via Roma 67, Pisa 56126, Italy.

出版信息

Ital J Pediatr. 2013 Feb 13;39:11. doi: 10.1186/1824-7288-39-11.

DOI:10.1186/1824-7288-39-11
PMID:23406772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3632492/
Abstract

Incomplete Kawasaki disease represents a diagnostic challenge for pediatricians. In the absence of classical presentation, the laboratoristic evaluation of systemic inflammation can help in placing the correct diagnosis to promptly start adequate therapy. Erythema multiforme is an acute, self-limiting condition considered to be a hypersensitivity reaction commonly associated with various infections or medications. This aspecific skin condition has been rarely described as a sign of Kawasaki disease. We report on the case of a 4 years old boy presenting high-grade fever associated with erythema multiforme and evidence of systemic inflammation who showed a good response to prompt treatment with intravenous immunoglobulins.

摘要

不典型川崎病对儿科医生来说是一个诊断挑战。在缺乏典型表现的情况下,系统炎症的实验室评估有助于正确诊断,从而及时开始适当的治疗。多形红斑是一种急性、自限性疾病,被认为是一种常见的与各种感染或药物相关的过敏反应。这种非特异性皮肤状况很少被描述为川崎病的一个迹象。我们报告了一例 4 岁男孩,表现为高热,伴有多形红斑和全身炎症证据,对及时静脉注射免疫球蛋白治疗反应良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a078/3632492/8c8c7777e327/1824-7288-39-11-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a078/3632492/5243d244861a/1824-7288-39-11-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a078/3632492/8c8c7777e327/1824-7288-39-11-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a078/3632492/5243d244861a/1824-7288-39-11-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a078/3632492/8c8c7777e327/1824-7288-39-11-2.jpg

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引用本文的文献

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本文引用的文献

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Pathogenic characterization of a cervical lymph node derived from a patient with Kawasaki disease.一名川崎病患者颈部淋巴结的病原学特征分析
Int J Clin Exp Pathol. 2012;5(8):814-23. Epub 2012 Oct 1.
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Kawasaki disease.川崎病。
Pediatr Clin North Am. 2012 Apr;59(2):425-45. doi: 10.1016/j.pcl.2012.03.009.
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Diagnosis of incomplete Kawasaki disease.不完全川崎病的诊断。
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Erythema multiforme in a child with Kawasaki disease.川崎病患儿的多形红斑
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Pediatr Cardiol. 2012 Oct;33(7):1097-103. doi: 10.1007/s00246-012-0232-9. Epub 2012 Feb 15.
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Complete and incomplete Kawasaki disease: two sides of the same coin.川崎病完全型与不完全型:同一疾病的两种表现。
Eur J Pediatr. 2012 Apr;171(4):657-62. doi: 10.1007/s00431-011-1631-2. Epub 2011 Dec 3.
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Atipical Kawasaki disease with coronary aneurysm in infant.婴儿川崎病不典型表现合并冠状动脉瘤。
Ital J Pediatr. 2011 Apr 17;37:19. doi: 10.1186/1824-7288-37-19.
7
Spectrum of kawasaki disease.川崎病的谱。
Indian J Pediatr. 2011 Apr;78(4):488-90. doi: 10.1007/s12098-010-0356-y. Epub 2010 Dec 31.
8
Erythema multiforme associated with Kawasaki Disease in a Korean child.
Eur J Dermatol. 2010 Jul-Aug;20(4):524-5. doi: 10.1684/ejd.2010.0972. Epub 2010 May 27.
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Atypical and incomplete Kawasaki disease.不典型川崎病。
Best Pract Res Clin Rheumatol. 2009 Oct;23(5):689-97. doi: 10.1016/j.berh.2009.08.010.
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Annular lesions in Kawasaki disease: a cause of confusion.川崎病中的环形病变:一个容易混淆的病因。
Australas J Dermatol. 2008 Nov;49(4):207-12. doi: 10.1111/j.1440-0960.2008.00470.x.