MMWR Morb Mortal Wkly Rep. 2013 Feb 15;62(6):108.
On August 16, 2012, the Colorado Department of Public Health and Environment was notified of two patients at an acute-care hospital in Denver with carbapenem-resistant Enterobacteriaceae (CRE), specifically Klebsiella pneumoniae (CRKP), isolated from respiratory specimens during July-August. Both isolates produced New Delhi metallo-beta-lactamase (NDM). A review of microbiology records identified a third patient with NDM-producing CRKP isolated from a respiratory specimen, admitted in May. Active surveillance cultures in September identified an additional five patients colonized with NDM-producing CRKP. An investigation was launched by the hospital and the Colorado Department of Public Health and Environment to guide infection control measures and limit transmission.
2012 年 8 月 16 日，科罗拉多州公共卫生和环境部接到丹佛一家急症医院的报告，称该院有两名患者感染了碳青霉烯类耐药肠杆菌科细菌（CRE），具体为克雷伯氏肺炎菌（CRKP），这些细菌于 7 月至 8 月期间从呼吸道标本中分离出来。两种分离物均产生新德里金属β-内酰胺酶（NDM）。微生物学记录审查发现，第三名患者 5 月入院时，从呼吸道标本中分离出携带 NDM 的 CRKP。9 月进行的主动监测培养发现，另外 5 名患者定植了携带 NDM 的 CRKP。医院和科罗拉多州公共卫生和环境部展开了调查，以指导感染控制措施并限制传播。
