2018 年至 2019 年，意大利托斯卡纳爆发新德里金属β-内酰胺酶产生的碳青霉烯类耐药肠杆菌科（NDM-CRE）。
Prolonged outbreak of New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019.
机构信息
Department of Translational Research and New technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Regional Health Agency of Tuscany, Florence, Italy.
出版信息
Euro Surveill. 2020 Feb;25(6). doi: 10.2807/1560-7917.ES.2020.25.6.2000085.
In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections and 246 (14.9%) infections/colonisations at other sites. were prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification and response resulted in sustained NDM-CRE transmission in the North-West area of Tuscany, but successfully contained spread within the region.
在意大利托斯卡纳，自 2018 年 11 月以来，产新德里金属β-内酰胺酶的碳青霉烯类耐药肠杆菌科细菌（NDM-CRE）有所增加。在 2018 年 11 月至 2019 年 10 月期间，有 1645 个样本呈 NDM-CRE 阳性：1270 例（77.2%）为肠道携带，129 例（7.8%）为血流感染，246 例（14.9%）为其他部位感染/定植。产 NDM-1 肠杆菌科细菌（1495 例；90.9%）普遍存在，ST147/NDM-1 是主要克隆。由于延迟发现和应对，导致托斯卡纳西北部地区的 NDM-CRE 持续传播，但成功控制了该地区的传播。
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