C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506, USA.
Org Biomol Chem. 2013 Mar 28;11(12):1917-20. doi: 10.1039/c3ob27452g. Epub 2013 Feb 13.
An efficient route for the preparation of substituted N-heterocycles was developed through the amine addition to nitroalkenes. The reaction tolerates a large substrate scope with good to excellent yields (up to 95%) and excellent stereoselectivities (up to 99 : 1 dr).
通过胺加成到硝基烯烃,开发了一种制备取代的 N-杂环的有效途径。该反应对大的底物范围具有良好到优异的收率(高达 95%)和极好的立体选择性(高达 99:1 dr)。